Browsing by Author "Helsby, Nuala"

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Title: Allantoin as a Biomarker of Inflammation in an Inflammatory Bowel Disease Mouse Model: NMR Analysis of Urine Author: Dryland, Philippa ; Love, Donald ; Walker, Michael ; Dommels, Y ; Butts, C ; Rowan, D ; Roy, NC ; Helsby, Nuala ; Browning, Brian ; Zhu, Shuotun ; Copp, Brent ; Ferguson, Lynnette Reference: Open Bioactive Compounds Journal, 1:1-6, 2008
Title: Can exercise influence Cyp2b10 function? Author: Jiang, Lanpeng (Kim) Date: (2023)
Title: The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation Author: Helsby, Nuala ; Hui, C-Y ; Goldthorpe, Michael ; Coller, JK ; Soh, MC ; Gow, PJ ; De Zoysa, JZ ; Tingle, Malcolm Reference: BRIT J CLIN PHARMACO 70(6):844-853 Dec 2010British Journal of clinical pharmacology 70(6):844-853 Dec 2010
Title: Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver Author: Dogra, M ; Palmer, Brian ; Bashiri, G ; Tingle, Malcolm ; Shinde, Sujata ; Anderson, Robert ; O'Toole, R ; Baker, Edward ; Denny, William ; Helsby, Nuala Reference: British Journal of Pharmacology 162(1):226-236 2011
Title: Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling. Author: Chua, Eng Wee ; Cree, Simone L ; Ton, Kim NT ; Lehnert, Klaus ; Shepherd, Phillip ; Helsby, Nuala ; Kennedy, Martin A Reference: Frontiers in Pharmacology 7:7 pages Article number 1 26 Jan 2016
Title: Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients. Author: Helsby, Nuala ; Yong, Minghan ; Burns, Kathryn ; Findlay, Michael ; Porter, David Reference: (2021). Cancer Chemotherapy and Pharmacology, 88(3), 533-542.
Title: CYP-catalysed cycling of clozapine and clozapine-N-oxide promotes the generation of reactive oxygen species in vitro Author: Kingston, Ellen ; Tingle, Malcolm ; Bellissima, Brandi L ; Helsby, Nuala ; Burns, Kathryn Reference: (2023). Xenobiotica, ahead-of-print(ahead-of-print), 1-12.
Title: CYP2C19 and CYP2D6 genotypes in Pacific peoples. Author: Helsby, Nuala Date: (2016-11)
Title: CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype. Author: Helsby, Nuala ; Lo, Wing Yee ; Sharples, K ; Riley, G ; Murray, M ; Spells, K ; DZHELAI, M ; Simpson, A ; Findlay, Michael Reference: BRITISH JOURNAL OF CANCER 99(8):1251-1255 14 Oct 2008
Title: Development of a QPCR-Block Assay to Quantify Platinum Drug Adducts In Vitro Author: O'Connell, Stephen Henry Date: (2021)
Title: Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin Author: Spicer, Julie ; Lena, G ; Lyons, DM ; Huttunen, KM ; Miller, Christian ; O'Connor, Patrick ; Bull, Matthew ; Helsby, Nuala ; Jamieson, Stephen ; Denny, William ; Ciccone, A ; Browne, KA ; Lopez, JA ; Rudd-Schmidt, J ; Voskoboinik, I ; Trapani, JA Reference: Journal of Medicinal Chemistry 56(23):9542-9555 2013
Title: Expression of key antioxidant enzymes as markers of early beta cell stress in pancreatic islets: Studies in human donor pancreas with newly diagnosed and long-term type 1 diabetes and without the disease Author: Pala, Kaaj Date: (2021)
Title: The genetic and epigenetic influences on pain after breast cancer surgery Author: Chiang, Daniel Date: (2020)
Title: Hepatic nitroreduction, toxicity and toxicokinetics of the anti-tumour prodrug CB 1954 in mouse and rat Author: Tang, Huen ; Helsby, Nuala ; Goldthorpe, Michael ; Thompson, Kyle ; Al-Ali, Saad ; Tingle, Malcolm Reference: TOXICOLOGY 240(1-2):70-85 30 Oct 2007
Title: High CYP2C19 phenotypic variability in gastrointestinal cancer patients Author: Burns, Kathryn ; Lo, WY ; Findlay, Michael ; Sharples, K ; Laking, George ; Helsby, Nuala Date: (2016-01)
Title: Identification of transporters of 5-fluorouracil Author: Burns-Maybury, Ursula Date: (2019)
Title: The importance of both CYP2C19 and CYP2B6 germline variations in cyclophosphamide pharmacokinetics and clinical outcomes. Author: Helsby, Nuala ; Yong, M ; van Kan, Maia ; de Zoysa, Janak ; Burns, Kathryn Date: (2019-09)
Title: Incidence and investigation of potential risk-factors for clozapine-associated myocarditis and cardiomyopathy in a New Zealand cohort. Author: Bellissima, Brandi L ; Vara, Alisha ; Helsby, Nuala ; Garavan, Fintan ; Tingle, Malcolm D Date: (2021-5)
Title: Indirect regulation of CYP2C19 gene expression via DNA methylation. Author: Burns, Kathryn ; Shepherd, Phillip ; Finlay, Graeme ; Tingle, Malcolm ; Helsby, Nuala Date: (2018-08)
Title: Influence of mustard group structure on pathways of in vitro metabolism of anticancer N-(2-hydroxyethyl)-3,5-dinitrobenzamide 2-mustard prodrugs. Author: Helsby, Nuala ; Goldthorpe, Michael ; Tang, Huen ; Atwell, Graham ; Smith, EM ; Wilson, William ; Tingle, Malcolm Reference: Drug Metabolism and Disposition 36(2):353-360 01 Feb 2008

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