Browsing by Subject "Xenograft Model Antitumor Assays"

Now showing items 1-18 of 18

Title: A novel human single-domain antibody-drug conjugate targeting CEACAM5 exhibits potent in vitro and in vivo antitumor activity Author: Zhu, Xiao-Yi ; Li, Quan-Xiao ; Kong, Yu ; Huang, Ke-Ke ; Wang, Gang ; Wang, Yun-Ji ; Lu, Jun ; Hua, Guo-Qiang ; Wu, Yan-Ling ; Ying, Tian-Lei Reference: (2024). Acta Pharmacologica Sinica, 45(3), 609-618.
Title: Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma. Author: Jiang, Dadi ; Tam, Arvin B ; Alagappan, Muthuraman ; Hay, Michael ; Gupta, Aparna ; Kozak, Margaret M ; Solow-Cordero, David E ; Lum, Pek Y ; Denko, Nicholas C ; Giaccia, Amato J ; Le, Quynh-Thu ; Niwa, Maho ; Koong, Albert C Date: (2016-09)
Title: Antibody-Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo. Author: Su, Dian ; Chen, Jinhua ; Cosino, Ely ; Dela Cruz-Chuh, Josefa ; Davis, Helen ; Del Rosario, Geoffrey ; Figueroa, Isabel ; Goon, Leanne ; He, Jintang ; Kamath, Amrita V ; Kaur, Surinder ; Kozak, Katherine R ; Lau, Jeffrey ; Lee, Donna ; Lee, M Violet ; Leipold, Douglas ; Liu, Luna ; Liu, Peter ; Lu, Guo-Liang ; Nelson, Chris ; Ng, Carl ; Pillow, Thomas H ; Polakis, Paul ; Polson, Andrew G ; Rowntree, Rebecca K ; Saad, Ola ; Safina, Brian ; Stagg, Nicola J ; Tercel, Moana ; Vandlen, Richard ; Vollmar, Breanna S ; Wai, John ; Wang, Tao ; Wei, BinQing ; Xu, Keyang ; Xue, Juanjuan ; Xu, Zijin ; Yan, Gang ; Yao, Hui ; Yu, Shang-Fan ; Zhang, Donglu ; Zhong, Fiona ; Dragovich, Peter S Date: (2019-05)
Title: Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. Author: Zhang, Yan ; Wu, Xishan ; Xue, Xiaoqian ; Li, Chenchang ; Wang, Junjian ; Wang, Rui ; Zhang, Cheng ; Wang, Chao ; Shi, Yudan ; Zou, Lingjiao ; Li, Qiu ; Huang, Zenghong ; Hao, Xiaojuan ; Loomes, Kerry ; Wu, Donghai ; Chen, Hong-Wu ; Xu, Jinxin ; Xu, Yong Reference: (2019). Journal of Medicinal Chemistry, 62(9), 4716-4730.
Title: Dynamin impacts homology-directed repair and breast cancer response to chemotherapy. Author: Chernikova, Sophia B ; Nguyen, Rochelle B ; Truong, Jessica T ; Mello, Stephano S ; Stafford, Jason H ; Hay, Michael ; Olson, Andrew ; Solow-Cordero, David E ; Wood, Douglas J ; Henry, Solomon ; von Eyben, Rie ; Deng, Lei ; Gephart, Melanie Hayden ; Aroumougame, Asaithamby ; Wiese, Claudia ; Game, John C ; Győrffy, Balázs ; Brown, J Martin Reference: Journal of clinical investigation 128(12):5307-5321 Dec 2018
Title: Engineering of Bone- and CD44-Dual-Targeting Redox-Sensitive Liposomes for the Treatment of Orthotopic Osteosarcoma. Author: Feng, Shuaishuai ; Wu, Zi-Xin ; Zhao, Ziyan ; Liu, Jinhu ; Sun, Kaoxiang ; Guo, Chuanyou ; Wang, Hongbo ; Wu, Zimei Date: (2019-02-07)
Title: Estrogen-functionalized liposomes grafted with glutathione-responsive sheddable chotooligosaccharides for the therapy of osteosarcoma. Author: Yin, Xuelei ; Feng, Shuaishuai ; Chi, Yingying ; Liu, Jinhu ; Sun, Kaoxiang ; Guo, Chuanyou ; Wu, Zimei Reference: Drug delivery 25(1):900-908 Nov 2018
Title: Hepatocyte nuclear factor 6 inhibits the growth and metastasis of cholangiocarcinoma cells by regulating miR-122. Author: Zhu, Huaqiang ; Mi, Yuetang ; Jiang, Xian ; Zhou, Xu ; Li, Rui ; Wei, Zheng ; Jiang, Hongchi ; Lu, Jun ; Sun, Xueying Date: (2016-05)
Title: <i>E. coli</i> nitroreductase NfsA is a reporter gene for non-invasive PET imaging in cancer gene therapy applications. Author: Mowday, Alexandra Marie ; Copp, Janine Naomi ; Syddall, Sophie Philippa ; Dubois, Ludwig Jerome ; Wang, Jingli ; Lieuwes, Natasja Gabi ; Biemans, Rianne ; Ashoorzadeh, Amir ; Abbattista, Maria Rosaria ; Williams, Elsie May ; Guise, Christopher Paul ; Lambin, Philippe ; Ackerley, David Francis ; Smaill, Jeff Bruce ; Theys, Jan ; Patterson, Adam Vorn Reference: (2020). Theranostics, 10(23), 10548-10562.
Title: A NAG-Guided Nano-Delivery System for Redox- and pH-Triggered Intracellularly Sequential Drug Release in Cancer Cells. Author: Liang, Yan ; Zhang, Jing ; Tian, Baocheng ; Wu, Zimei ; Svirskis, Darren ; Han, Jingtian Reference: International journal of nanomedicine 15:841-855 Jan 2020
Title: A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Author: Harikumar, KB ; Kunnumakkara, AB ; Ochi, N ; Tong, Z ; Deorukhkar, A ; Sung, B ; Kelland, L ; Jamieson, Stephen ; Sutherland, R ; Raynham, T ; Charles, M ; Bagherzadeh, A ; Foxton, C ; Boakes, A ; Farooq, M ; Maru, D ; Diagaradjane, P ; Matsuo, Y ; Sinnett-Smith, J ; Gelovani, J ; Krishnan, S ; Aggarwal, BB ; Rozengurt, E ; Ireson, CR ; Guha, S Reference: Molecular Cancer Therapeutics 9(5):1136-1146 May 2010
Title: Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors. Author: Hicks, Kevin ; Siim, BG ; Jaiswal, Jagdish ; Pruijn, Frederik ; Fraser, AM ; Patel, R ; Hogg, A ; Liyanage, HD ; Dorie, MJ ; Brown, JM ; Denny, William ; Hay, Michael ; Wilson, William Reference: Clinical Cancer Research 16(20):4946-4957 Oct 2010
Title: PIK3CA-mutated melanoma cells rely on cooperative signaling through mTORC1/2 for sustained proliferation. Author: Silva, Jillian M ; Deuker, Marian M ; Baguley, Bruce ; McMahon, Martin Date: (2017-05)
Title: Pre-clinical activity of PR-104 as monotherapy and in combination with sorafenib in hepatocellular carcinoma Author: Abbattista, Maria ; Jamieson, Stephen ; Gu, Yongchuan ; Nickel, JE ; Pullen, Susan ; Patterson, Adam ; Wilson, William ; Guise, Christopher Reference: Cancer Biology and Therapy 16(4):610-622 Apr 2015
Title: Precise tuning of gene expression levels in mammalian cells. Author: Michaels, Yale S ; Barnkob, Mike B ; Barbosa, Hector ; Baeumler, Toni A ; Thompson, Mary K ; Andre, Violaine ; Colin-York, Huw ; Fritzsche, Marco ; Gileadi, Uzi ; Sheppard, Hilary M ; Knapp, David JHF ; Milne, Thomas A ; Cerundolo, Vincenzo ; Fulga, Tudor A Reference: (2019). Nature Communications, 10(1), 818-.
Title: Redox-sensitive and hyaluronic acid functionalized liposomes for cytoplasmic drug delivery to osteosarcoma in animal models. Author: Chi, Yingying ; Yin, Xuelei ; Sun, Kaoxiang ; Feng, Shuaishuai ; Liu, Jinhu ; Chen, Daquan ; Guo, Chuanyou ; Wu, Zimei Date: (2017-09)
Title: Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer. Author: Sun, JD ; Liu, Q ; Wang, J ; Ahluwalia, D ; Ferraro, D ; Wang, Y ; Duan, JX ; Ammons, WS ; Curd, JG ; Matteucci, MD ; Hart, CP Reference: Clin Cancer Res 18(3):758-770 01 Feb 2012
Title: Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP-TEAD complex. Author: Wei, Honglong ; Wang, Fuhai ; Wang, Yong ; Li, Tao ; Xiu, Peng ; Zhong, Jingtao ; Sun, Xueying ; Li, Jie Reference: Cancer science 108(3):478-487 Mar 2017

Now showing items 1-18 of 18

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