Expectation and the Placebo Effect in Inflammatory Skin Reactions

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dc.contributor.advisor Broadbent, E en
dc.contributor.advisor Booth, R en
dc.contributor.author Darragh, Margot en
dc.date.accessioned 2011-12-15T21:44:14Z en
dc.date.issued 2011 en
dc.identifier.uri http://hdl.handle.net/2292/10096 en
dc.description Full text is available to authenticated members of The University of Auckland only. en
dc.description.abstract reaction (weal size and symptoms). During the experiment a number of questionnaires measuring stress, mood, perceptions, and expectation were administered. Self-reported symptoms were assessed along with the physiological measures of weal size and heart rate. The two main outcome variables were weal size and symptom reporting as generated by the histamine-induced skin reaction. Results showed that the manipulation of expectation was successful with a lower expected weal size in the expectancy group as compared to the control group, but there was no difference in expected symptoms. There was no difference between groups in weal size, or symptoms reported, but there was a significant decrease in heart rate in the expectancy group after manipulation of expectation. Given the contextual cues and the nature of the information provided to participants regarding heart rate, this finding is thought to be attributable to an expectation-induced placebo effect. Relationships were also found between symptom reporting and negative arousal (current mood state), perceived stress, and heart rate. The findings from this study indicate that while an expectation-induced placebo effect on skin reactivity was not demonstrated, it does not necessarily indicate that this is not possible. The methodological limitations associated with administration of the skin reactivity test, as well as those associated with the manipulation of expectation, may have impeded demonstration of this effect. The modulation of skin reactivity by expectation may be possible and future research should be carried out to investigate this with the noted limitations addressed. The modulation of heart rate demonstrated in this study should be replicated and extended with the aim of investigating mechanisms that might be involved. en
dc.publisher ResearchSpace@Auckland en
dc.relation.ispartof Masters Thesis - University of Auckland en
dc.relation.isreferencedby UoA99239834814002091 en
dc.rights Restricted Item. Available to authenticated members of The University of Auckland. en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/nz/ en
dc.title Expectation and the Placebo Effect in Inflammatory Skin Reactions en
dc.type Thesis en
thesis.degree.discipline Health Psychology en
thesis.degree.grantor The University of Auckland en
thesis.degree.level Masters en
dc.rights.holder Copyright: The author en
pubs.elements-id 261907 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Population Health en
pubs.org-id Gen.Practice& Primary Hlthcare en
pubs.record-created-at-source-date 2011-12-16 en

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