dc.contributor.author |
Orosco, MM |
en |
dc.contributor.author |
Pacholski, C |
en |
dc.contributor.author |
Miskelly, Gordon |
en |
dc.contributor.author |
Sailor, MJ |
en |
dc.date.accessioned |
2012-01-31T20:33:40Z |
en |
dc.date.issued |
2006 |
en |
dc.identifier.citation |
Advanced Materials 18(11):1393-1396 2006 |
en |
dc.identifier.issn |
0935-9648 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/10833 |
en |
dc.description.abstract |
An optical biosensor for protease activity, capable of detecting picomole quantities of protease, is constructed from a 1D photonic crystal of porous Si. The porous Si layer is coated with a thin film of zein, a natural hydrophobic protein. Proteolytic cleavage produces small fragments that infiltrate the pores of the photonic crystal, producing a distinct color change (see figure). The amount of protease pepsin used on each of the spots is indicated. |
en |
dc.publisher |
WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
en |
dc.relation.ispartofseries |
Advanced Materials |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0935-9648/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Protein-Coated Porous-Silicon Photonic Crystals for Amplified Optical Detection of Protease Activity |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1002/adma.200502420 |
en |
pubs.issue |
11 |
en |
pubs.begin-page |
1393 |
en |
pubs.volume |
18 |
en |
dc.rights.holder |
Copyright: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
en |
pubs.end-page |
1396 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
65995 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Chemistry |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |