dc.contributor.author | Clark, George | en |
dc.contributor.author | Falshaw, A | en |
dc.contributor.author | Gainsford, GJ | en |
dc.contributor.author | Lensink, C | en |
dc.contributor.author | Slade, Angela | en |
dc.contributor.author | Wright, Leonard | en |
dc.date.accessioned | 2012-02-26T22:33:23Z | en |
dc.date.issued | 2010 | en |
dc.identifier.citation | Journal of Coordination Chemistry 63(3):373-393 2010 | en |
dc.identifier.issn | 0095-8972 | en |
dc.identifier.uri | http://hdl.handle.net/2292/12014 | en |
dc.description.abstract | Treatment of [RuCl2(COD)]n with the chiral diphosphinite ligand (1S,2S)-1,2-trans-bis-(O-diphenylphosphino)cyclohexane [(1S,2S)-14] and triethylamine gives the bis(diphosphinite) complex RuHCl[(1S,2S)-14]2 (15) in good yield. If (rac)-1,2-trans-bis-(O-diphenylphosphino)cyclohexane [(rac)-14] is used in place of (1S,2S)-14 in this reaction, a racemic mixture of RuHCl[(1S,2S)-14]2 and RuHCl[(1R,2R)-14]2 [(rac)-16] is formed. The X-ray crystal structure of (rac)-16 center dot(2.5CH2Cl2) has been determined. Treatment of (rac)-16 with hydrogen in iso-propanol leads to the formation of a racemic mixture of RuH2[(1S,2S)-14]2 and RuH2[(1R,2R)-14]2 [(rac)-17]. The structure of (rac)-17 was confirmed by the X-ray analysis of a racemic crystal. Ruthenium mono(diphosphinite), diamine complexes of the general formula RuCl2(NN)(PP) are formed by the treatment of RuCl2(PPh3)3 with the appropriate diphosphinite (PP) and diamine (NN) ligands. In this way, the following complexes have been synthesized: RuCl2[(+)-DPEN][(1S,2S)-14] (18), RuCl2[(-)-DPEN][(1S,2S)-14] (19), RuCl2[(+)-DPEN][(1R,2R)-14] (20), RuCl2[(-)-DPEN][(1R,2R)-14] (21), RuCl2[(+)-DPEN][(rac)-14] (22), RuCl2[(-)-DPEN][(rac)-14] (23), RuCl2(D-NN2)[(1S,2S)-14] (24), RuCl2(EDA)[(1S,2S)-14] (25), RuCl2(D-NN2)(D-10) (26), RuCl2(EDA)(D-10) (27), RuCl2[(+)-DPEN](D-10Et) (28), RuCl2(D-NN2)(D-10Et) (29), [where DPEN = 1,2-diphenylethylenediamine, D-NN2 = 1D-1,2-dideoxy-1,2-diamino-3,4,5,6-tetra-O-benzyl-myo-inositol, EDA = 1,2-diaminoethane, D-10 = 1D-3,4-bis(O-diphenylphosphino)-1,2,5,6-tetra-O-methyl-chiro-inositol, D-10Et = 1D-3,4-bis(O-diphenylphosphino)-1,2,5,6-tetra-O-ethyl-chiro-inositol]. These ruthenium complexes catalyze the hydrogenation of the ketones acetophenone and 3-quinuclidinone to give the corresponding alcohols in high yields, but with moderate to low enantiomeric excesses. | en |
dc.language | EN | en |
dc.publisher | TAYLOR & FRANCIS LTD | en |
dc.relation.ispartofseries | Journal of Coordination Chemistry | en |
dc.rights | Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from: http://www.sherpa.ac.uk/romeo/issn/0095-8972/ | en |
dc.rights.uri | https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm | en |
dc.subject | Ruthenium | en |
dc.subject | Catalytic asymmetric hydrogenation of ketones | en |
dc.subject | Chiro-inositol | en |
dc.subject | Chiral diphosphinite ligand | en |
dc.subject | X-ray crystal structure | en |
dc.subject | CARBOHYDRATE PHOSPHINITES | en |
dc.subject | PHOSPHORUS LIGANDS | en |
dc.subject | NOBEL LECTURE | en |
dc.subject | KETONES | en |
dc.subject | HYDROFORMYLATION | en |
dc.subject | PRECATALYSTS | en |
dc.subject | DERIVATIVES | en |
dc.subject | REACTIVITY | en |
dc.title | Ruthenium complexes of chiral diphosphinite ligands with cyclohexane or chiro-inositol backbones as catalysts for asymmetric hydrogenation reactions | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1080/00958970903502744 | en |
pubs.issue | 3 | en |
pubs.begin-page | 373 | en |
pubs.volume | 63 | en |
dc.rights.holder | Copyright: TAYLOR & FRANCIS LTD | en |
pubs.end-page | 393 | en |
dc.rights.accessrights | http://purl.org/eprint/accessRights/RestrictedAccess | en |
pubs.subtype | Article | en |
pubs.elements-id | 98890 | en |
pubs.org-id | Science | en |
pubs.org-id | Chemistry | en |
dc.identifier.pii | 918233346 | en |
pubs.record-created-at-source-date | 2010-09-01 | en |