dc.contributor.author |
Baker, Daniel |
en |
dc.contributor.author |
Brauner, CJ |
en |
dc.date.accessioned |
2012-02-26T23:39:22Z |
en |
dc.date.issued |
2012 |
en |
dc.identifier.citation |
Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology 161(1):61-68 2012 |
en |
dc.identifier.issn |
1095-6433 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/12044 |
en |
dc.description.abstract |
CO2 tolerance in white sturgeon is associated with the ability to tightly regulate intracellular pH (pHi) despite a large reduction in extracellular pH (pHe) termed preferential pHi regulation. How this regulatory response affects whole animal metabolic rate is unknown. Accordingly, we characterized oxygen consumption rate () and metabolically-relevant organismal and cellular responses in white sturgeon during exposure to hypercarbia. White sturgeon were able to protect intracellular pH (pHi) in liver and white muscle as early as 6 h (the earliest time period investigated) following exposure to severe (sub-lethal) hypercarbia (45 and 90 mmHg PCO2). Sturgeon exposed to 15 and 30 mmHg PCO2 exhibited pHe compensation and significant increases in (up to 80% greater than control values). In contrast, severe hypercarbia (≥ 45 mmHg PCO2) elicited an uncompensated reduction in pHe (up to ~ 1.0 pH units) and red blood cells (as great as ~ 0.5 pH units), and was accompanied by 30 and 60% reductions in , respectively. While behavioral, respiratory and cellular responses to hypercarbia were observed, none corresponded well with the pattern or magnitude of changes in . The findings of this research provide empirical support for the hypothesis that preferential pHi regulation is not metabolically costly, and thus may have been a strategy strongly selected for in fishes encountering short-term hypercarbia. |
en |
dc.publisher |
Elsevier |
en |
dc.relation.ispartofseries |
Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology |
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dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
Detail obtained from http://www.sherpa.ac.uk/romeo/issn/1095-6433/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Hypercarbia |
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dc.title |
Metabolic changes associated with acid–base regulation during hypercarbia in the CO2-tolerant chondrostean, white sturgeon (Acipenser transmontanus) |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.cbpa.2011.09.002 |
en |
pubs.issue |
1 |
en |
pubs.begin-page |
61 |
en |
pubs.volume |
161 |
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dc.rights.holder |
Copyright: Elsevier |
en |
pubs.end-page |
68 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
233829 |
en |
pubs.record-created-at-source-date |
2011-10-19 |
en |