dc.contributor.author |
Knowles, Sarah |
en |
dc.contributor.author |
Davis, SR |
en |
dc.contributor.author |
Beattie, EM |
en |
dc.contributor.author |
Thomas, NL |
en |
dc.contributor.author |
Burrett, AK |
en |
dc.contributor.author |
Ward, HE |
en |
dc.contributor.author |
Stanfield, AM |
en |
dc.contributor.author |
Biswas, M |
en |
dc.contributor.author |
Ankersmit-Udy, AE |
en |
dc.contributor.author |
Oxley, PE |
en |
dc.contributor.author |
Barnett, JL |
en |
dc.contributor.author |
Pearson, JF |
en |
dc.contributor.author |
van der Does, Y |
en |
dc.contributor.author |
MacGibbon, AHF |
en |
dc.contributor.author |
Spelman, RJ |
en |
dc.contributor.author |
Lehnert, Klaus |
en |
dc.contributor.author |
Snell, Russell |
en |
dc.date.accessioned |
2012-02-27T00:07:34Z |
en |
dc.date.issued |
2009-07 |
en |
dc.identifier.citation |
Genetics 182(3):923-926 Jul 2009 |
en |
dc.identifier.issn |
0016-6731 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/12056 |
en |
dc.description.abstract |
β-Carotene biochemistry is a fundamental process in mammalian biology. Aberrations either through malnutrition or potentially through genetic variation may lead to vitamin A deficiency, which is a substantial public health burden. In addition, understanding the genetic regulation of this process may enable bovine improvement. While many bovine QTL have been reported, few of the causative genes and mutations have been identified. We discovered a QTL for milk b-carotene and subsequently identified a premature stop codon in bovine b-carotene oxygenase 2 (BCO2), which also affects serum b-carotene content. The BCO2 enzyme is thereby identified as a key regulator of β-carotene metabolism. |
en |
dc.language |
EN |
en |
dc.publisher |
Genetics Society of America |
en |
dc.relation.ispartofseries |
Genetics |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from: http://www.sherpa.ac.uk/romeo/issn/0016-6731/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
VITAMIN-A |
en |
dc.subject |
IN-VIVO |
en |
dc.subject |
CLEAVAGE |
en |
dc.subject |
IDENTIFICATION |
en |
dc.subject |
ENZYME |
en |
dc.subject |
QTL |
en |
dc.subject |
YIELD |
en |
dc.subject |
GENE |
en |
dc.title |
Mutation in Bovine beta-Carotene Oxygenase 2 Affects Milk Color |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1534/genetics.109.101741 |
en |
pubs.issue |
3 |
en |
pubs.begin-page |
923 |
en |
pubs.volume |
182 |
en |
dc.rights.holder |
Copyright: Genetics Society of America |
en |
dc.identifier.pmid |
19398771 |
en |
pubs.end-page |
926 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
118298 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Biological Sciences |
en |
pubs.record-created-at-source-date |
2012-02-22 |
en |
pubs.dimensions-id |
19398771 |
en |