dc.contributor.author |
Curtis, Maurice |
en |
dc.contributor.author |
Kam, Monica |
en |
dc.contributor.author |
Nannmark, U |
en |
dc.contributor.author |
Anderson, MF |
en |
dc.contributor.author |
Axell, MZ |
en |
dc.contributor.author |
Wikkelso, C |
en |
dc.contributor.author |
Holtas, S |
en |
dc.contributor.author |
Van Roon-Mom, WM |
en |
dc.contributor.author |
Bjork-Eriksson, T |
en |
dc.contributor.author |
Nordborg, C |
en |
dc.contributor.author |
Frisen, J |
en |
dc.contributor.author |
Dragunow, Michael |
en |
dc.contributor.author |
Faull, Richard |
en |
dc.contributor.author |
Eriksson, PS |
en |
dc.date.accessioned |
2012-03-07T02:35:50Z |
en |
dc.date.issued |
2007 |
en |
dc.identifier.citation |
Science 315(5816):1243-1248 2007 |
en |
dc.identifier.issn |
0036-8075 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/13208 |
en |
dc.description.abstract |
The rostral migratory stream (RMS) is the main pathway by which newly born subventricular zone cells reach the olfactory bulb (OB) in rodents. However, the RMS in the adult human brain has been elusive. We demonstrate the presence of a human RMS, which is unexpectedly organized around a lateral ventricular extension reaching the OB, and illustrate the neuroblasts in it. The RMS ensheathing the lateral olfactory ventricular extension, as seen by magnetic resonance imaging, cell-specific markers, and electron microscopy, contains progenitor cells with migratory characteristics and cells that incorporate 5-bromo-2′-deoxyuridine and become mature neurons in the OB. |
en |
dc.publisher |
American Association for the Advancement of Science |
en |
dc.relation.ispartofseries |
Science |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0036-8075/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1126/science.1136281 |
en |
pubs.issue |
5816 |
en |
pubs.begin-page |
1243 |
en |
pubs.volume |
315 |
en |
dc.rights.holder |
Copyright: American Association for the Advancement of Science |
en |
dc.identifier.pmid |
17303719 |
en |
pubs.end-page |
1248 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
80619 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Anatomy and Medical Imaging |
en |
pubs.org-id |
Pharmacology |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Biological Sciences |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |
pubs.dimensions-id |
17303719 |
en |