Synthesis of the southern FGHI ring system of azaspiracid-1 and investigation into the controlling elements of C28- and C36-ketalization

Zhou, XT; Lu, L; Furkert, Daniel; Wells, CE; Carter, RG

dc.contributor.author	Zhou, XT	en
dc.contributor.author	Lu, L	en
dc.contributor.author	Furkert, Daniel	en
dc.contributor.author	Wells, CE	en
dc.contributor.author	Carter, RG	en
dc.date.accessioned	2012-03-11T22:53:41Z	en
dc.date.issued	2006	en
dc.identifier.citation	Angewandte Chemie (International ed.) 45(45):7622-7626 2006	en
dc.identifier.issn	1433-7851	en
dc.identifier.uri	http://hdl.handle.net/2292/13744	en
dc.description.abstract	Heading south: An efficient approach to the FGHI southern ring system of azaspiracid-1 is disclosed. Each of the eight stereogenic centers is generated with excellent diastereoselectivity. In addition, the stereochemical outcome of the ketalization steps could be controlled by careful selection of the conditions. Teoc=2-(trimethylsilyl)ethoxycarbonyl; TMS=trimethylsilyl; TIPS=triisopropylsilyl; Bn=benzyl.	en
dc.language	EN	en
dc.publisher	Wiley-VCH Verlag GmbH & Co.	en
dc.relation.ispartofseries	Angewandte Chemie International Edition	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1433-7851/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.subject	aldol reaction	en
dc.subject	azaspiracids	en
dc.subject	fused-ring systems	en
dc.subject	ketalization	en
dc.subject	natural products	en
dc.subject	HETERO-MICHAEL ADDITION	en
dc.subject	STRUCTURAL ELUCIDATION	en
dc.subject	BIS-SPIROCYCLIZATION	en
dc.subject	C28-C40 FRAGMENTS	en
dc.subject	CHEMICAL-SHIFTS	en
dc.subject	MYTILUS-EDULIS	en
dc.subject	PART 1	en
dc.subject	CONSTRUCTION	en
dc.subject	DOMAIN	en
dc.subject	ABCD	en
dc.title	Synthesis of the southern FGHI ring system of azaspiracid-1 and investigation into the controlling elements of C28- and C36-ketalization	en
dc.type	Journal Article	en
dc.identifier.doi	10.1002/anie.200603353	en
pubs.issue	45	en
pubs.begin-page	7622	en
pubs.volume	45	en
dc.rights.holder	Copyright: Wiley-VCH Verlag GmbH & Co.	en
dc.identifier.pmid	17044107	en
pubs.end-page	7626	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	112759	en
pubs.org-id	Science	en
pubs.org-id	Chemistry	en
pubs.record-created-at-source-date	2012-02-16	en
pubs.dimensions-id	17044107	en