dc.contributor.author |
Petousis-Harris, Helen |
en |
dc.coverage.spatial |
Netherlands |
en |
dc.date.accessioned |
2012-03-22T20:42:40Z |
en |
dc.date.issued |
2008-11-25 |
en |
dc.identifier.citation |
Vaccine 26(50):6299-6304 25 Nov 2008 |
en |
dc.identifier.issn |
0264-410X |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/15127 |
en |
dc.description.abstract |
There are inconsistencies in recommendations and practice with regards to how best to administer vaccines. This review evaluates the literature on intramuscular vaccine administration technique in primarily paediatric populations and concludes from available evidence which aspects of vaccine administration are associated with reactogenicity. Variables with best evidence to support practice to reduce reactogenicity were: Site of injection--less reactogenicity has been noted when the buttock is used rather than the thigh; tissue (muscle or subcutaneous)--less reactions are noted when vaccine is administered intramuscularly rather than subcutaneously; length of needle--longer needles are associated with less reactogenicity. Angle of injection--a 90 degrees angle is associated with less reactogenicity than a reduced angle. Despite a need for more empirical studies, there appears to be several vaccine administration techniques relating to needle angle, length, site and depth of injection that result in fewer reactions and these could be considered for public health policy, in conjunction with immunogenicity. |
en |
dc.language |
eng |
en |
dc.publisher |
Elsevier |
en |
dc.relation.ispartofseries |
Vaccine |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0264-410X/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Child |
en |
dc.subject |
Child, Preschool |
en |
dc.subject |
Humans |
en |
dc.subject |
Infant |
en |
dc.subject |
Injections, Intramuscular |
en |
dc.subject |
Injections, Subcutaneous |
en |
dc.subject |
Vaccination |
en |
dc.subject |
Vaccines |
en |
dc.title |
Vaccine injection technique and reactogenicity--evidence for practice. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.vaccine.2008.08.052 |
en |
pubs.issue |
50 |
en |
pubs.begin-page |
6299 |
en |
pubs.volume |
26 |
en |
dc.rights.holder |
Copyright: Elsevier |
en |
dc.identifier.pmid |
18804137 |
en |
pubs.end-page |
6304 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Review |
en |
pubs.elements-id |
303056 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Population Health |
en |
pubs.org-id |
Gen.Practice& Primary Hlthcare |
en |
dc.identifier.pii |
S0264-410X(08)01201-2 |
en |
pubs.record-created-at-source-date |
2012-03-23 |
en |
pubs.dimensions-id |
18804137 |
en |