Denosumab for prevention of fractures in postmenopausal women with osteoporosis

Cummings, SR; Martin, JS; McClung, MR; Siris, ES; Eastell, R; Reid, Ian; Delmas, PD; Austin, Matthew; Wang, A; Kutilek, S; Adami, S; Zanchetta, J; Libanati, C; Siddhanti, S; Christiansen, C; Zoog, HB

dc.contributor.author	Cummings, SR	en
dc.contributor.author	Martin, JS	en
dc.contributor.author	McClung, MR	en
dc.contributor.author	Siris, ES	en
dc.contributor.author	Eastell, R	en
dc.contributor.author	Reid, Ian	en
dc.contributor.author	Delmas, PD	en
dc.contributor.author	Austin, Matthew	en
dc.contributor.author	Wang, A	en
dc.contributor.author	Kutilek, S	en
dc.contributor.author	Adami, S	en
dc.contributor.author	Zanchetta, J	en
dc.contributor.author	Libanati, C	en
dc.contributor.author	Siddhanti, S	en
dc.contributor.author	Christiansen, C	en
dc.contributor.author	Zoog, HB	en
dc.date.accessioned	2012-03-25T22:06:09Z	en
dc.date.issued	2009	en
dc.identifier.citation	New England Journal of Medicine 361:756-765 2009	en
dc.identifier.issn	0028-4793	en
dc.identifier.uri	http://hdl.handle.net/2292/15244	en
dc.description.abstract	Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor-κB ligand (RANKL) that blocks its binding to RANK, inhibiting the development and activity of osteoclasts, decreasing bone resorption, and increasing bone density. Given its unique actions, denosumab may be useful in the treatment of osteoporosis.	en
dc.publisher	Massachusetts Medical Society	en
dc.relation.ispartofseries	New England Journal of Medicine	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0028-4793/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.title	Denosumab for prevention of fractures in postmenopausal women with osteoporosis	en
dc.type	Journal Article	en
dc.identifier.doi	10.1056/NEJMoa0809493	en
pubs.begin-page	756	en
pubs.volume	361	en
dc.rights.holder	Copyright: Massachusetts Medical Society	en
dc.identifier.pmid	19671655	en
pubs.end-page	765	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	86110	en
pubs.org-id	Medical and Health Sciences	en
pubs.org-id	School of Medicine	en
pubs.org-id	Medicine Department	en
pubs.org-id	Science	en
pubs.org-id	Science Research	en
pubs.org-id	Maurice Wilkins Centre (2010-2014)	en
pubs.record-created-at-source-date	2010-09-01	en
pubs.dimensions-id	19671655	en