Denosumab for prevention of fractures in postmenopausal women with osteoporosis

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Show simple item record Cummings, SR en Martin, JS en McClung, MR en Siris, ES en Eastell, R en Reid, Ian en Delmas, PD en Austin, Matthew en Wang, A en Kutilek, S en Adami, S en Zanchetta, J en Libanati, C en Siddhanti, S en Christiansen, C en Zoog, HB en 2012-03-25T22:06:09Z en 2009 en
dc.identifier.citation New England Journal of Medicine 361:756-765 2009 en
dc.identifier.issn 0028-4793 en
dc.identifier.uri en
dc.description.abstract Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor-κB ligand (RANKL) that blocks its binding to RANK, inhibiting the development and activity of osteoclasts, decreasing bone resorption, and increasing bone density. Given its unique actions, denosumab may be useful in the treatment of osteoporosis. en
dc.publisher Massachusetts Medical Society en
dc.relation.ispartofseries New England Journal of Medicine en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.title Denosumab for prevention of fractures in postmenopausal women with osteoporosis en
dc.type Journal Article en
dc.identifier.doi 10.1056/NEJMoa0809493 en
pubs.begin-page 756 en
pubs.volume 361 en
dc.rights.holder Copyright: Massachusetts Medical Society en
dc.identifier.pmid 19671655 en
pubs.end-page 765 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 86110 en Medical and Health Sciences en School of Medicine en Medicine Department en Science en Science Research en Maurice Wilkins Centre (2010-2014) en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 19671655 en

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