Is eczema really on the increase worldwide?

Show simple item record Williams, H en Stewart, Alistair en von Mutius, E en Cookson, WO en Anderson, HR en and the ISAAC Phase One and Three Study Groups en Clayton, Tadd en Mitchell, Edwin en Asher, Monica Innes en Ellwood, Philippa en 2012-03-08T19:05:26Z en 2012-03-25T22:46:33Z en 2008 en
dc.identifier.citation Journal of Allergy and Clinical Immunology 121(4):947-954 01 Apr 2008 en
dc.identifier.issn 0091-6749 en
dc.identifier.uri en
dc.description.abstract Background: It is unclear whether eczema prevalence is truly increasing worldwide. Objective: We sought to investigate worldwide secular trends in childhood eczema. Methods: Children (n 5 302,159) aged 13 to 14 years in 105 centers from 55 countries and children aged 6 to 7 years (n5187,943) in 64 centers from 35 countries were surveyed from the same study centers taking part in Phase One and Three of the International Study of Asthma and Allergies in Childhood by using identical validated and translated questionnaires. Eczema was defined as an itchy, relapsing, flexural skin rash in the last 12 months, and it was termed severe eczema when it was associated with 1 or more disturbed nights per week. Results: Annual prevalence changes in relation to average prevalence across Phase One and Three were generally small and differed in direction according to the age of the participants and world region. For children 13 to 14 years old, eczema symptom prevalence decreased in some previously highprevalence centers from the developed world, such as the United Kingdom and New Zealand, whereas centers with previously high prevalence rates from developing countries continued to increase. In the children 6 to 7 years old, most centers showed an increase in current eczema symptoms. Similar patterns to these were present for severe eczema at both ages. Conclusion: The epidemic of eczema seems to be leveling or decreasing in some countries with previously high prevalence rates. The picture elsewhere is mixed, with many formerly low-prevalence developing countries experiencing substantial increases, especially in the younger age group. en
dc.publisher Elsevier en
dc.relation.ispartofseries Journal of Allergy and Clinical Immunology en
dc.relation.replaces en
dc.relation.replaces 2292/13465 en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from: en
dc.rights.uri en
dc.title Is eczema really on the increase worldwide? en
dc.type Journal Article en
dc.identifier.doi 10.1016/j.jaci.2007.11.004 en
pubs.issue 4 en
pubs.begin-page 947 en
pubs.volume 121 en
dc.rights.holder American Academy of Allergy, Asthma & Immunology en
dc.identifier.pmid 18155278 en
pubs.end-page 954 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 98775 en Medical and Health Sciences en School of Medicine en Paediatrics Child & Youth Hlth en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 18155278 en

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