Plasma urocortin 1 in human heart failure.

Wright, SP; Doughty, Robert; Frampton, CM; Gamble, Gregory; Yandle, TG; Richards, AM

dc.contributor.author	Wright, SP	en
dc.contributor.author	Doughty, Robert	en
dc.contributor.author	Frampton, CM	en
dc.contributor.author	Gamble, Gregory	en
dc.contributor.author	Yandle, TG	en
dc.contributor.author	Richards, AM	en
dc.coverage.spatial	United States	en
dc.date.accessioned	2012-03-26T02:30:21Z	en
dc.date.issued	2009	en
dc.identifier.citation	Circulation: Heart Failure 2(5):465-471 2009	en
dc.identifier.uri	http://hdl.handle.net/2292/15354	en
dc.description.abstract	The urocortins are emerging as potentially important contributors to neurohumoral regulation of the circulation with recent reports attributing a powerful array of hemodynamic, renal, and neurohumoral effects to the urocortins in cardiac failure. These peptides also seem to have cardioprotective effects in the setting of ischemia-reperfusion. Little is known concerning the plasma concentrations of the urocortins in health and disease. We have investigated plasma urocortin 1 as a potential diagnostic marker of heart failure and documented its relationships to symptoms, measures of cardiac function, and concurrent levels of other circulating neurohormones.	en
dc.language	eng	en
dc.publisher	American Heart Association, Inc	en
dc.relation.ispartofseries	Circulation: Heart Failure	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.subject	Adrenomedullin	en
dc.subject	Adult	en
dc.subject	Aged	en
dc.subject	Aged, 80 and over	en
dc.subject	Biological Markers	en
dc.subject	Creatinine	en
dc.subject	Endothelin-1	en
dc.subject	Female	en
dc.subject	Heart Failure	en
dc.subject	Humans	en
dc.subject	Logistic Models	en
dc.subject	Male	en
dc.subject	Middle Aged	en
dc.subject	Natriuretic Peptides	en
dc.subject	Predictive Value of Tests	en
dc.subject	Prospective Studies	en
dc.subject	ROC Curve	en
dc.subject	Severity of Illness Index	en
dc.subject	Up-Regulation	en
dc.subject	Urocortins	en
dc.subject	Ventricular Function, Left	en
dc.title	Plasma urocortin 1 in human heart failure.	en
dc.type	Journal Article	en
dc.identifier.doi	10.1161/CIRCHEARTFAILURE.108.840207	en
pubs.issue	5	en
pubs.begin-page	465	en
pubs.volume	2	en
dc.rights.holder	Copyright: American Heart Association, Inc.	en
dc.identifier.pmid	19808377	en
pubs.end-page	471	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	117870	en
pubs.org-id	Medical and Health Sciences	en
pubs.org-id	School of Medicine	en
pubs.org-id	Medicine Department	en
dc.identifier.eissn	1941-3297	en
dc.identifier.pii	CIRCHEARTFAILURE.108.840207	en
pubs.record-created-at-source-date	2012-07-30	en
pubs.dimensions-id	19808377	en