Inhibin and premature ovarian failure.

Show simple item record Chand, AL en Harrison, CA en Shelling, Andrew en
dc.coverage.spatial England en 2012-03-28T23:22:55Z en 2010-01 en
dc.identifier.citation Human Reproduction Update 16(1):39-50 Jan 2010 en
dc.identifier.issn 1355-4786 en
dc.identifier.uri en
dc.description.abstract Elucidation of the causes of premature ovarian failure (POF) is difficult due to the heterogeneity of the condition. Inhibin is a potential candidate gene for POF based on its dual actions on FSH secretion by the pituitary and gametogenesis in the gonads. A missense mutation in the inhibin alpha subunit gene (INHA G769A) is associated with POF in several populations. However, there is phenotypic heterogeneity in INHA G769A mutation carriers. en
dc.language eng en
dc.publisher Oxford University Press en
dc.relation.ispartofseries Human Reproduction Update en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from: en
dc.rights.uri en
dc.subject Amino Acid Sequence en
dc.subject Female en
dc.subject Genetic Predisposition to Disease en
dc.subject Heterozygote en
dc.subject Humans en
dc.subject Inhibins en
dc.subject Molecular Sequence Data en
dc.subject Mutation, Missense en
dc.subject Phenotype en
dc.subject Primary Ovarian Insufficiency en
dc.subject Protein Structure, Tertiary en
dc.subject Sequence Alignment en
dc.title Inhibin and premature ovarian failure. en
dc.type Journal Article en
dc.identifier.doi 10.1093/humupd/dmp031 en
pubs.issue 1 en
pubs.begin-page 39 en
pubs.volume 16 en
dc.rights.holder Copyright: Oxford University Press en
dc.identifier.pmid 19752047 en
pubs.end-page 50 en
dc.rights.accessrights en
pubs.subtype Review en
pubs.elements-id 118409 en Medical and Health Sciences en School of Medicine en Obstetrics and Gynaecology en
dc.identifier.eissn 1460-2369 en
dc.identifier.pii dmp031 en
pubs.record-created-at-source-date 2012-03-29 en
pubs.dimensions-id 19752047 en

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