Breast cancer and spaceflight: Risk and management

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dc.contributor.author Barr, Yael R en
dc.contributor.author Bacal, Kira en
dc.contributor.author Jones, Jeffrey A en
dc.contributor.author Hamilton, Douglas R en
dc.date.accessioned 2012-03-29T19:17:11Z en
dc.date.issued 2007-04-01 en
dc.identifier.citation Aviation, Space, and Environmental Medicine 78(4):A26-A37 01 Apr 2007 en
dc.identifier.issn 0095-6562 en
dc.identifier.uri http://hdl.handle.net/2292/15992 en
dc.description.abstract Spaceflight exposes astronauts to a host of environmental factors which could increase their risk for cancer. Epidemiological studies have shown an increased incidence of breast cancer in female commercial flight attendants, with occupational risk factors as one of the proposed mechanisms for the higher incidence in this cohort. Since female astronauts are exposed to similar occupational conditions as flight attendants, they too may be at an increased risk for breast cancer. With the planning of exploration class missions to the Moon and to Mars it is important to assess and minimize the risk for breast malignancy, and to have a well-defined protocol for the diagnosis and treatment of a breast mass discovered during a mission. Risk factors for development of breast cancer in the female astronaut include ionizing radiation, disrupted melatonin homeostasis secondary to circadian shifting, chemical exposure, and changes in immune function. Preflight, in-flight, and postflight screening and management modalities include imaging and fine needle aspiration (FNA). Employing such a strategy may provide a viable management approach in the case of a newly diagnosed breast mass in-flight. en
dc.language English en
dc.publisher Aerospace Medical Association en
dc.relation.ispartofseries Aviation, Space, and Environmental Medicine en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0095-6562/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.subject Science & Technology en
dc.subject Life Sciences & Biomedicine en
dc.subject Public, Environmental & Occupational Health en
dc.subject Medicine, General & Internal en
dc.subject Sport Sciences en
dc.subject General & Internal Medicine en
dc.subject fine needle aspiration en
dc.subject FNA en
dc.subject spaceflight en
dc.subject radiation en
dc.subject AIRLINE CABIN ATTENDANTS en
dc.subject DEPOT-MEDROXYPROGESTERONE ACETATE en
dc.subject RANDOMIZED CONTROLLED TRIALS en
dc.subject RESIDENTIAL MAGNETIC-FIELDS en
dc.subject FEMALE FLIGHT ATTENDANTS en
dc.subject EPSTEIN-BARR-VIRUS en
dc.subject SPACE-FLIGHT en
dc.subject AROMATASE INHIBITORS en
dc.subject POSTMENOPAUSAL WOMEN en
dc.subject POOLED ANALYSIS en
dc.title Breast cancer and spaceflight: Risk and management en
dc.type Journal Article en
pubs.issue 4 en
pubs.begin-page A26 en
pubs.volume 78 en
dc.rights.holder Copyright: Aerospace Medical Association en
pubs.author-url http://www.ingentaconnect.com/content/asma/asem/2007/00000078/A00104s1/art00006?token=005c1cce931f7bd13fc2405847447b494a2f783f6a422c4774474833757e6f7c385d592f3f3b578a0ce51d005de5 en
pubs.end-page A37 en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Review en
pubs.elements-id 243546 en
pubs.record-created-at-source-date 2012-08-30 en


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