Neurogenesis in humans

Show simple item record Curtis, MA en Kam, Monica en Faull, RLM en 2012-04-10T21:58:17Z en 2011 en
dc.identifier.citation European Journal of Neuroscience 33(6):1170-1174 2011 en
dc.identifier.issn 0953-816X en
dc.identifier.uri en
dc.description.abstract Since 1944 increasing evidence has been emerging that the adult human brain harbours progenitor cells with the potential to produce neuroblasts. However, it was not until 1998 that this fact was confirmed in the adult human brain. With the purpose of human neurogenesis being hotly debated, many research groups have focussed on the effect of neurodegenerative diseases in the brain to determine the strength of the endogenous regenerative response. Although most of the human studies have focussed on the hippocampus, there is a groundswell of evidence that there is greater plasticity in the subventricular zone and in the ventriculo-olfactory neurogenic system. In this review, we present the evidence for increased or decreased plasticity and neurogenesis in different diseases and with different drug treatments in the adult human brain. Whilst there is a paucity of studies on human neurogenesis, there are sufficient to draw some conclusions about the potential of plasticity in the human brain. en
dc.publisher Blackwell Publishing en
dc.relation.ispartofseries European Journal of Neuroscience en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.title Neurogenesis in humans en
dc.type Journal Article en
dc.identifier.doi 10.1111/j.1460-9568.2011.07616.x en
pubs.issue 6 en
pubs.begin-page 1170 en
pubs.volume 33 en
dc.rights.holder Copyright: the authors; European Journal of Neuroscience; Federation of European Neuroscience Societies; Blackwell Publishing Ltd en
pubs.end-page 1174 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 260728 en Science en Biological Sciences en
dc.identifier.eissn 1460-9568 en
pubs.record-created-at-source-date 2011-12-14 en

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