Perianal fistulae in Crohn's Disease: current and future approaches to treatment.

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dc.contributor.author Keshaw, Hussila en
dc.contributor.author Foong, KS en
dc.contributor.author Forbes, A en
dc.contributor.author Day, RM en
dc.coverage.spatial United States en
dc.date.accessioned 2012-04-11T21:09:52Z en
dc.date.issued 2010 en
dc.identifier.citation Inflammatory Bowel Diseases 16(5):870-880 2010 en
dc.identifier.issn 1536-4844 en
dc.identifier.uri http://hdl.handle.net/2292/17056 en
dc.description.abstract Perianal fistulae are common in Crohn's disease but rarely heal without treatment. The main aim of treatment is to effectively close the fistula without affecting sphincter integrity and continence. Traditional surgical and medical approaches are not without their limitations and may result in either comorbidity, such as fecal incontinence, or incomplete healing of the fistulae. Over the last 2 decades these limitations have led to a paradigm shift toward the use of biomaterials, and more recently cell-based therapies, which have met with variable degrees of success. This review discusses the traditional and current methods of treatment, as well as emerging and possible alternative approaches that may improve fistula healing. en
dc.language eng en
dc.publisher John Wiley & Sons, Inc. en
dc.relation.ispartofseries Inflammatory Bowel Diseases en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1078-0998/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.subject Anti-Bacterial Agents en
dc.subject Crohn Disease en
dc.subject Humans en
dc.subject Immunosuppressive Agents en
dc.subject Rectal Fistula en
dc.title Perianal fistulae in Crohn's Disease: current and future approaches to treatment. en
dc.type Journal Article en
dc.identifier.doi 10.1002/ibd.21137 en
pubs.issue 5 en
pubs.begin-page 870 en
pubs.volume 16 en
dc.rights.holder Copyright: Crohn’s & Colitis Foundation of America, Inc en
dc.identifier.pmid 19834976 en
pubs.end-page 880 en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Review en
pubs.elements-id 222967 en
pubs.record-created-at-source-date 2012-04-12 en
pubs.dimensions-id 19834976 en


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