dc.contributor.author |
Kingston, Richard |
en |
dc.contributor.author |
Lo, VL |
en |
dc.contributor.author |
Millane, Rick |
en |
dc.date.accessioned |
2012-04-12T01:52:33Z |
en |
dc.date.issued |
2009 |
en |
dc.identifier.citation |
Acta Crystallographica A65:312-318 2009 |
en |
dc.identifier.issn |
0108-7673 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/17131 |
en |
dc.description.abstract |
An algorithm is described for determining macromolecular envelopes from crystal diffraction amplitudes measured from a solvent contrast variation series. The method uses solvent contrast variation data that have been preprocessed to represent the structure-factor amplitudes of the envelope. The amplitudes are phased using an iterative projection algorithm that incorporates connectivity and compactness constraints on the envelope. The algorithm is tested by simulation on two protein envelopes and shown to be effective even in the absence of the very low resolution data, which are difficult to access experimentally. |
en |
dc.publisher |
Wiley-Blackwell Publishing, Inc. |
en |
dc.relation.ispartofseries |
Acta Crystallographica Section A: Foundations of Crystallography |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0108-7673/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Determination of molecular envelopes from solvent contrast variation data |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1107/S0108767309019047 |
en |
pubs.begin-page |
312 |
en |
pubs.volume |
A65 |
en |
dc.rights.holder |
Copyright: International Union of Crystallography |
en |
dc.identifier.pmid |
19535852 |
en |
pubs.end-page |
318 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
91738 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Biological Sciences |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |
pubs.dimensions-id |
19535852 |
en |