Spatial localization of A2E in the retinal pigment epithelium.

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dc.contributor.author Grey, Angus en
dc.contributor.author Crouch, RK en
dc.contributor.author Koutalos, Y en
dc.contributor.author Schey, KL en
dc.contributor.author Ablonczy, Z en
dc.coverage.spatial United States en
dc.date.accessioned 2012-04-27T02:31:13Z en
dc.date.issued 2011-06 en
dc.identifier.citation Investigative Ophthalmology & Visual Science 52(7):3926-3933 Jun 2011 en
dc.identifier.issn 0146-0404 en
dc.identifier.uri http://hdl.handle.net/2292/17587 en
dc.description.abstract Lipofuscin, a fluorescent lysosomal pigment made of lipophilic molecules, is associated with age-related pathophysiological processes in the retinal pigment epithelium (RPE). The best-characterized components of lipofuscin are A2E and its oxides, but a direct spatial correlation with lipofuscin has not previously been possible. en
dc.language eng en
dc.publisher The Association for Research in Vision and Ophthalmology, Inc. en
dc.relation.ispartofseries Investigative Ophthalmology & Visual Science en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0146-0404/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.subject ATP-Binding Cassette Transporters en
dc.subject Animals en
dc.subject Female en
dc.subject Lipofuscin en
dc.subject Macular Degeneration en
dc.subject Male en
dc.subject Mice en
dc.subject Mice, 129 Strain en
dc.subject Mice, Mutant Strains en
dc.subject Microscopy, Fluorescence en
dc.subject Oxidation-Reduction en
dc.subject Oxides en
dc.subject Pyridinium Compounds en
dc.subject Retinal Pigment Epithelium en
dc.subject Retinoids en
dc.subject Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization en
dc.title Spatial localization of A2E in the retinal pigment epithelium. en
dc.type Journal Article en
dc.identifier.doi 10.1167/iovs.10-7020 en
pubs.issue 7 en
pubs.begin-page 3926 en
pubs.volume 52 en
dc.rights.holder Copyright: The Association for Research in Vision and Ophthalmology, Inc. en
dc.identifier.pmid 21357388 en
pubs.end-page 3933 en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Article en
pubs.elements-id 206837 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Medical Sciences en
pubs.org-id Physiology Division en
dc.identifier.pii iovs.10-7020 en
pubs.record-created-at-source-date 2012-04-27 en
pubs.dimensions-id 21357388 en


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