dc.contributor.author |
Donnelly, E |
en |
dc.contributor.author |
Williams, RM |
en |
dc.contributor.author |
Downs, SA |
en |
dc.contributor.author |
Dickinson, Michelle |
en |
dc.contributor.author |
Baker, SP |
en |
dc.contributor.author |
van der Meulen, MC |
en |
dc.date.accessioned |
2012-05-30T00:37:47Z |
en |
dc.date.issued |
2006 |
en |
dc.identifier.citation |
Journal of Materials Research 21(8):2106-2117 2006 |
en |
dc.identifier.issn |
0884-2914 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/18753 |
en |
dc.description.abstract |
Cancellous bone plays a crucial structural role in the skeleton, yet little is known about the microstructure-mechanical property relationships of the tissue at the microscale. Cancellous tissue is characterized by a microstructure consisting of layers interspaced with transition zones with different proportions of collagen and mineral. In this study, the quasistatic and dynamic mechanical properties of lamellar and interlamellar tissue in human vertebrae were assessed with nanoindentation, and the collagen content and organization were characterized with second harmonic generation microscopy. Lamellar tissue was 35% stiffer, 25% harder, and had a 13% lower loss tangent relative to interlamellar tissue. The stiff, hard lamellae corresponded to areas of highly ordered, collagen-rich material, with a relatively low loss tangent, whereas the compliant, soft interlamellar regions corresponded to areas of disordered or collagen-poor material. These data suggest an important role for collagen in the tissue-level mechanical properties of bone. |
en |
dc.publisher |
Cambridge University Press; Materials Research Society |
en |
dc.relation.ispartofseries |
Journal of Materials Research |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0884-2914/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Quasistatic and dynamic nanomechanical properties of cancellous bone tissue relate to collagen content and organization |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1557/jmr.2006.0259 |
en |
pubs.issue |
8 |
en |
pubs.begin-page |
2106 |
en |
pubs.volume |
21 |
en |
dc.rights.holder |
Copyright: Cambridge University Press; Materials Research Society |
en |
pubs.end-page |
2117 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
93216 |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |