Flucloxacillin treatment of Staphylococcus aureus meningitis

Show simple item record

dc.contributor.author Ritchie, Stephen en
dc.contributor.author Rupali, P en
dc.contributor.author Roberts, SA en
dc.contributor.author Thomas, Mark en
dc.date.accessioned 2012-06-26T03:37:58Z en
dc.date.issued 2007 en
dc.identifier.citation EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 26(7):501-504 01 Jul 2007 en
dc.identifier.issn 0934-9723 en
dc.identifier.uri http://hdl.handle.net/2292/19163 en
dc.description.abstract In this paper, we aimed to evaluate the efficacy of flucloxacillin treatment of meningitis caused by methicillin-sensitive Staphylococcus aureus. We identified 33 patients with meningitis due to S. aureus; eight had community-acquired meningitis and 25 had neurosurgical meningitis. Six of the eight patients with communityacquired meningitis were cured. Eighteen of the 22 patients treated with flucloxacillin were cured without relapse (86%, 95%CI 65–97%) and their cerebrospinal fluid (CSF) cultures were sterile after a median of 3 days of treatment. The cure rate for 12 patients who also received an additional antibiotic at the outset of treatment was 75% (95%CI 43–95%). This was not different to the cure rate for the ten patients who received flucloxacillin alone 90% (95%CI 56–100%). We conclude that flucloxacillin is an effective treatment for meningitis caused by S. aureus. en
dc.publisher Springer-Verlag en
dc.relation.ispartofseries European Journal of Clinical Microbiology & Infectious Diseases en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0934-9723/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title Flucloxacillin treatment of Staphylococcus aureus meningitis en
dc.type Journal Article en
dc.identifier.doi 10.1007/s10096-007-0324-2 en
pubs.issue 7 en
pubs.begin-page 501 en
pubs.volume 26 en
dc.rights.holder Copyright: Springer-Verlag en
dc.identifier.pmid 17554568 en
pubs.end-page 504 en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Article en
pubs.elements-id 72136 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Medical Sciences en
pubs.org-id Molecular Medicine en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 17554568 en

Files in this item

There are no files associated with this item.

Find Full text

This item appears in the following Collection(s)

Show simple item record


Search ResearchSpace