dc.contributor.author |
Ritchie, Stephen |
en |
dc.contributor.author |
Rupali, P |
en |
dc.contributor.author |
Roberts, SA |
en |
dc.contributor.author |
Thomas, Mark |
en |
dc.date.accessioned |
2012-06-26T03:37:58Z |
en |
dc.date.issued |
2007 |
en |
dc.identifier.citation |
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 26(7):501-504 01 Jul 2007 |
en |
dc.identifier.issn |
0934-9723 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/19163 |
en |
dc.description.abstract |
In this paper, we aimed to evaluate the efficacy of flucloxacillin treatment of meningitis caused by methicillin-sensitive Staphylococcus aureus. We identified 33 patients with meningitis due to S. aureus; eight had community-acquired meningitis and 25 had neurosurgical meningitis. Six of the eight patients with communityacquired meningitis were cured. Eighteen of the 22 patients treated with flucloxacillin were cured without relapse (86%, 95%CI 65–97%) and their cerebrospinal fluid (CSF) cultures were sterile after a median of 3 days of treatment. The cure rate for 12 patients who also received an additional antibiotic at the outset of treatment was 75% (95%CI 43–95%). This was not different to the cure rate for the ten patients who received flucloxacillin alone 90% (95%CI 56–100%). We conclude that flucloxacillin is an effective treatment for meningitis caused by S. aureus. |
en |
dc.publisher |
Springer-Verlag |
en |
dc.relation.ispartofseries |
European Journal of Clinical Microbiology & Infectious Diseases |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0934-9723/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Flucloxacillin treatment of Staphylococcus aureus meningitis |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1007/s10096-007-0324-2 |
en |
pubs.issue |
7 |
en |
pubs.begin-page |
501 |
en |
pubs.volume |
26 |
en |
dc.rights.holder |
Copyright: Springer-Verlag |
en |
dc.identifier.pmid |
17554568 |
en |
pubs.end-page |
504 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
72136 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Molecular Medicine |
en |
pubs.record-created-at-source-date |
2010-09-01 |
en |
pubs.dimensions-id |
17554568 |
en |