dc.contributor.advisor |
Smith, H |
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dc.contributor.author |
Villamonte, Romina |
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dc.date.accessioned |
2013-03-17T19:07:45Z |
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dc.date.issued |
2013 |
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dc.identifier.uri |
http://hdl.handle.net/2292/20284 |
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dc.description |
Full text is available to authenticated members of The University of Auckland only. |
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dc.description.abstract |
Prior heavy exercise bout on cycle ergometer changes the V O2 kinetics of a subsequent heavy exercise bout. These changes are an increase in V O2 fundamental component (Ap) and a reduction in V O2 slow component (V O2sc) without changing primary component time constant. Infusion of epinephrine has shown to increase resting V O2 levels in humans at rest and during exercise. To test the effect of epinephrine on V O2 kinetics, epinephrine was injected at the beginning of exercise and the kinetics of oxygen consumption was compared with the oxygen kinetics of a prior and second exercise bouts. Seven healthy physically active male participants volunteered for the study. Participants performed 8 min bout of heavy exercise on an electrically braked cycle ergometer preceded by 1) 8 min heavy exercise bout with a 6 min rest period in between and 2) 0.10 mg epinephrine intra muscular injection on deltoid immediately followed by 5 minutes rest to reach it’s onset of action. Same protocol was performed in two different days. Bloods samples to measure plasma [Epi] and [NE] were taken ten times in total during each testing day. Fundamental amplitude (Ap) of epinephrine bout was significantly higher than the prior cycling bout (p < 0.05). Slow component of oxygen uptake (As’) was significantly lower in the second cycling bout (222 + 77.4 mlO2*min-1) compared to the prior cycling bout (369.4 + 135.4 mlO2*min-1;p < 0.05) and to epinephrine cycling bout (357.1 + 178.6 mlO2*min-1; p = 0.05). [Epi] at end of epinephrine bout was significantly higher when compared to blood samples taken, pre-prior, 2-min into prior, pre-second, 2-min into second and pre-Epi injection (p < 0.05). The results of the study demonstrate that epinephrine injection increased magnitude of Ap and V O2end compared to prior heavy bout. However, it had no effect on V O2 baseline, effective time constant, or V O2sc compared to prior heavy bout. No significance differences were found in V O2 kinetics when comparing second heavy bout and epinephrine injection heavy bout. Results show that the increase in [Epi] may be responsible in part for the changes seen in V O2 kinetics of second heavy exercise bout. |
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dc.publisher |
ResearchSpace@Auckland |
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dc.relation.ispartof |
Masters Thesis - University of Auckland |
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dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
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dc.rights |
Restricted Item. Available to authenticated members of The University of Auckland. |
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dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
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dc.rights.uri |
http://creativecommons.org/licenses/by-nc-nd/3.0/nz/ |
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dc.title |
Effect of epinephrine on slow component of oxygen consumption during heavy exercise |
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dc.type |
Thesis |
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thesis.degree.grantor |
The University of Auckland |
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thesis.degree.level |
Masters |
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dc.rights.holder |
Copyright: The Author |
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pubs.elements-id |
374365 |
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pubs.record-created-at-source-date |
2013-03-18 |
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dc.identifier.wikidata |
Q112901811 |
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