Assessment of contrast sensitivity of patients with macular disease using reduced contrast near visual acuity charts

Abstract

A set of near Bailey-Lovie logMAR letter charts that varied in contrast from 0.40 dB (C = 0.95) to 58.0 dB (C=0.001) were used to measure the middle and high spatial frequency range of the contrast sensitivity function (CSF) of 15 subjects with age-related maculopathy (ARM) and 15 age-matched normal subjects. The letter charts were shown to have good test-retest reliability. Compared with measures made using CRT generated square wave gratings of variable contrast and spatial frequency they were also shown to provide a valid measure of CSF in the mid to high spatial frequency range. The 20.0 dB letter chart alone was shown to be a good screening device for macular disease. The letter charts do not provide a measure of the peak of the CSF and a supplementary test of contrast sensitivity is needed to quantify contrast sensitivity at a low spatial frequency. Three measures are proposed as necessary to document foveal visual capability of patients with macular disease: distance logMAR visual acuity to measure high spatial frequency resolution, visual acuity with letter charts of 20 dB contrast to assess mid spatial frequency resolution; and contrast sensitivity for the detection of an edge to estimate contrast sensitivity for larger objects.