Superantigens - powerful modifiers of the immune system

Show simple item record Fraser, John en Arcus, VL en Kong, P en Baker, Edward en Proft, Thomas en 2013-10-02T22:10:44Z en 2000 en
dc.identifier.citation Molecular Medicine Today 6(3):125-132 01 Mar 2000 en
dc.identifier.issn 1357-4310 en
dc.identifier.uri en
dc.description.abstract Superantigens are powerful microbial toxins that activate the immune system by binding to class II major histocompatibility complex and T-cell receptor molecules. They cause a number of diseases characterized by fever and shock and are important virulence factors for two human commensal organisms, Staphylococcus aureus and Streptococcus pyogenes, as well as for some viruses. Their mode of action and variation around the common theme of over-stimulating T cells, provides a rich insight into the constant battle between microbes and the immune system. en
dc.relation.ispartofseries Molecular Medicine Today en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri en
dc.title Superantigens - powerful modifiers of the immune system en
dc.type Journal Article en
dc.identifier.doi 10.1016/S1357-4310(99)01657-3 en
pubs.issue 3 en
pubs.begin-page 125 en
pubs.volume 6 en
dc.identifier.pmid 10689316 en
pubs.end-page 132 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 38814 en Medical and Health Sciences en Medical Sciences en Molecular Medicine en Science en Science Research en Maurice Wilkins Centre (2010-2014) en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 10689316 en

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