Autocatalytic Sets and Biological Specificity

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Show simple item record Hordijk, W en Wills, Peter en Steel, M en 2014-01-27T21:35:50Z en 2013 en
dc.identifier.citation Bulletin of Mathematical Biology 76(1):201-224 2013 en
dc.identifier.issn 0092-8240 en
dc.identifier.uri en
dc.description.abstract A universal feature of the biochemistry of any living system is that all the molecules and catalysts that are required for reactions of the system can be built up from an available food source by repeated application of reactions from within that system. RAF (reflexively autocatalytic and food-generated) theory provides a formal way to study such processes. Beginning with Kauffman's notion of "collectively autocatalytic sets," this theory has been further developed over the last decade with the discovery of efficient algorithms and new mathematical analysis. In this paper, we study how the behaviour of a simple binary polymer model can be extended to models where the pattern of catalysis more precisely reflects the ligation and cleavage reactions involved. We find that certain properties of these models are similar to, and can be accurately predicted from, the simple binary polymer model; however, other properties lead to slightly different estimates. We also establish a number of new results concerning the structure of RAFs in these systems. © 2013 Society for Mathematical Biology. en
dc.relation.ispartofseries Bulletin of Mathematical Biology en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.title Autocatalytic Sets and Biological Specificity en
dc.type Journal Article en
dc.identifier.doi 10.1007/s11538-013-9916-4 en
pubs.issue 1 en
pubs.begin-page 201 en
pubs.volume 76 en
dc.identifier.pmid 24233808 en
pubs.end-page 224 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 410828 en Science en Physics en
dc.identifier.eissn 1522-9602 en
pubs.record-created-at-source-date 2014-01-28 en
pubs.dimensions-id 24233808 en

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