Abstract:
Choline is an essential nutrient and an integral component of several fundamental neurochemical processes. This chapter will provide an overview of the biochemistry of choline, its biosynthetic pathways, role as a dietary nutrient, and involvement in phospholipid metabolism. Metabolic changes that occur in conditions affecting the biosynthesis of phospholipids and cellular membrane integrity (e.g., neoplasms and neurological disorders) are discussed within the context of magnetic resonance spectroscopy.