dc.contributor.author |
Kenealy, Timothy |
en |
dc.contributor.author |
Elley, Carolyn |
en |
dc.contributor.author |
Collins, John |
en |
dc.contributor.author |
Moyes, Simon |
en |
dc.contributor.author |
Metcalf, Patricia |
en |
dc.contributor.author |
Drury, PL |
en |
dc.date.accessioned |
2015-01-06T22:59:41Z |
en |
dc.date.issued |
2012 |
en |
dc.identifier.citation |
Nephrology Dialysis Transplantation, 2012, 27 (5), pp. 1840 - 1846 (7) |
en |
dc.identifier.issn |
0931-0509 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/23956 |
en |
dc.description.abstract |
BACKGROUND: A high incidence of albuminuria, varying by ethnicity, has been found in a number of populations worldwide. There have been few opportunities to explore the prevalence of albuminuria as a marker of chronic kidney disease while adjusting for other risk factors in the different ethnic groups in New Zealand.METHODS: We examined the association between albuminuria and ethnicity using cross-sectional data from a large cohort study of type 2 diabetes conducted in New Zealand.RESULTS: The study population was 65 171 adults in primary care with type 2 diabetes, not on renal replacement therapy; median age was 64.7 years, median diabetes duration 5.1 years and 48.5% were non-European. Microalbuminuria or greater was present in 50% of Maori, 49% of Pacific people, 31% of Indo- and East-Asians and 28% of Europeans. Regression analyses were used to examine the association between ethnicity and albuminuria-measured as albumin:creatinine ratio-after controlling for study site and other known risk variables: age, sex, duration of diabetes, smoking status, socioeconomic status, body mass index, systolic and diastolic blood pressure, triglyceride levels, HbA(1C) and being on an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker. After controlling for these risk factors and compared with Europeans, odds ratios for 'advanced' albuminuria (≥100 mg/mmol) were 3.9 (95% confidence interval: 3.2-4.6) in Maori, 4.7 (3.6-6.3) in Pacific people, 2.0 (1.5-2.7) in Indo-Asians and 4.1 (3.2-5.1) in East-Asians.CONCLUSION: Non-European ethnicities appear to carry significantly higher risks of albuminuria in type 2 diabetes. |
en |
dc.language |
Eng |
en |
dc.publisher |
The Author(s) and ERA-EDTA |
en |
dc.relation.ispartofseries |
Nephrology Dialysis Transplantation |
en |
dc.relation.replaces |
2292/13196 |
en |
dc.relation.replaces |
http://hdl.handle.net/2292/13196 |
en |
dc.relation.replaces |
2292/13196 |
en |
dc.relation.replaces |
http://hdl.handle.net/2292/13196 |
en |
dc.relation.replaces |
2292/13196 |
en |
dc.relation.replaces |
http://hdl.handle.net/2292/13196 |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0931-0509/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Increased prevalence of albuminuria among non-European peoples with type 2 diabetes |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1093/ndt/gfr540 |
en |
pubs.issue |
5 |
en |
pubs.begin-page |
1840 |
en |
pubs.volume |
27 |
en |
dc.identifier.pmid |
21917731 |
en |
pubs.end-page |
1846 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
198196 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Population Health |
en |
pubs.org-id |
Gen.Practice& Primary Hlthcare |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Statistics |
en |
dc.identifier.eissn |
1460-2385 |
en |
dc.identifier.pii |
gfr540 |
en |
pubs.record-created-at-source-date |
2012-02-16 |
en |
pubs.dimensions-id |
21917731 |
en |