The frequency and nature of drug administration error during anaesthesia

Show simple item record Webster, Craig en Merry, Alan en Larsson, L en McGrath, KA en Weller, Jennifer en 2015-02-19T20:54:13Z en 2001 en
dc.identifier.citation Anaesthesia and Intensive Care, 2001, 29 (5), pp. 494 - 500 (7) en
dc.identifier.issn 0310-057X en
dc.identifier.uri en
dc.description.abstract We aimed to establish the frequency and nature of drug administration error in anaesthesia (a significant subset of error in medicine) at two hospitals. Anaesthetists were asked to return a study form anonymouslyfor every anaesthetic, indicating whether or not a drug administration error or pre-error (defined as any incident with potential to become an error) had occurred. Further details were sought if the response was affirmative. From 10,806 anaesthetics, 7794 study forms were returned, representing response rates of 80% from Hospital A and 57% from Hospital B (72% overall). The frequency (95% confidence intervals) of drug administration error; of any type, per anaesthetic was 0.0075 (0.006 to 0.009), of i.v. bolus errors was 0.005 (0.0035 to 0.006) and of pre-errors was 0.004 (0.003 to 0.005), with no significant difference between hospitals. Overall, one drug administration error was reported for every 133 anaesthetics. The two largest individual categories of error involved incorrect doses (20%) and substitutions (20%) with i.v. boluses of drug. Of the i.v. bolus substitutions, 69% occurred between different pharmacological classes. One patient was aware while under muscle relaxation, and two required prolonged ventilation. In addition, 47 transient physiological effects were reported, of which five required intervention. We conclude that drug administration error during anaesthesia is considerably more frequent than previously reported. en
dc.relation.ispartofseries Anaesthesia and Intensive Care en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.title The frequency and nature of drug administration error during anaesthesia en
dc.type Journal Article en
pubs.issue 5 en
pubs.begin-page 494 en
pubs.volume 29 en
dc.identifier.pmid 11669430 en
pubs.end-page 500 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 36404 en Medical and Health Sciences en School of Medicine en Cent Medical & Hlth Sci Educat en
dc.identifier.eissn 1448-0271 en
pubs.record-created-at-source-date 2010-09-01 en
pubs.dimensions-id 11669430 en

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