dc.contributor.author |
Dirven, S |
en |
dc.contributor.author |
Xu, PW |
en |
dc.contributor.author |
Cheng, Leo |
en |
dc.contributor.author |
Allen, J |
en |
dc.date.accessioned |
2015-03-30T20:08:18Z |
en |
dc.date.issued |
2014 |
en |
dc.identifier.citation |
IEEE Transactions on Instrumentation and Measurement, 2014, 64 (4), pp. 967 - 974 |
en |
dc.identifier.issn |
0018-9456 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/25001 |
en |
dc.description.abstract |
The relationships among bolus formulation, engineering rheometric quantities, and peristaltic transport effects are examined in this paper. Investigation of a series of synthetic bolus materials and swallowing strategies is conducted using a novel peristaltic swallowing robot inspired by esophageal swallowing, which manifests as a benchtop rheological instrument. To determine the validity of biomimetic swallowing, manometry, a clinical technique for capturing swallowing pressure profiles is used to establish congruence between the robotic findings and those of a clinical nature. To determine the contribution of the bolus and swallowing strategy to the intraluminal pressure signature (ILPS), three parameters were varied: peristaltic wave velocity (20, 30, 40 mm s-1), wavefront length (40, 50, and 60 mm) and starch thickener (Nutulis, Nutricia) concentration (25, 50, 75, 100, and 150 g L-1) were investigated. Wave velocity and starch-based bolus formulation concentration were found to exhibit the most profound changes in the intrabolus pressure signatures. The highest bolus tail pressure gradient of 0.33 kPa mm-1 was achieved with a 150 g L-1 bolus formulation being transported at 40 mm s-1 with a wavefront length of 60 mm. In each dimension, the relationship between the parameters and features of the manometric pressure signature are found to be nonlinear owing to the shear-thinning, non-Newtonian nature of the model bolus fluid. The robotic ILPSs are synonymous with those of a clinical nature, suggesting that the swallowing robot has merit as a novel, biologically inspired, bolus investigation tool external to the human body. |
en |
dc.relation.ispartofseries |
IEEE Transactions on Instrumentation and Measurement |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.ieee.org/publications_standards/publications/rights/rights_policies.html http://www.sherpa.ac.uk/romeo/issn/0018-9456/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Biomimetic investigation of intrabolus pressure signatures by a peristaltic swallowing robot |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1109/TIM.2014.2360800 |
en |
pubs.issue |
4 |
en |
pubs.begin-page |
967 |
en |
pubs.volume |
64 |
en |
pubs.end-page |
974 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
458858 |
en |
pubs.org-id |
Bioengineering Institute |
en |
pubs.org-id |
ABI Associates |
en |
pubs.org-id |
Engineering |
en |
pubs.org-id |
Mechanical Engineering |
en |
dc.identifier.eissn |
1557-9662 |
en |
pubs.record-created-at-source-date |
2014-10-21 |
en |