Quality assessment for VMAT prostate radiotherapy planning based on data envelopment analysis

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dc.contributor.author Lin, KL en
dc.contributor.author Simpson, J en
dc.contributor.author Sasso, P en
dc.contributor.author Raith, Andrea en
dc.contributor.author Ehrgott, Matthias en
dc.date.accessioned 2015-05-20T23:55:42Z en
dc.date.issued 2013-08-21 en
dc.identifier.citation Physics in Medicine and Biology, 2013, 58 (16), pp. 5753 - 5769 en
dc.identifier.issn 0031-9155 en
dc.identifier.uri http://hdl.handle.net/2292/25592 en
dc.description.abstract The majority of commercial radiotherapy treatment planning systems requires planners to iteratively adjust the plan parameters in order to find a satisfactory plan. This iterative trial-and-error nature of radiotherapy treatment planning results in an inefficient planning process and in order to reduce such inefficiency, plans can be accepted without achieving the best attainable quality. We propose a quality assessment method based on data envelopment analysis (DEA) to address this inefficiency. This method compares a plan of interest to a set of past delivered plans and searches for evidence of potential further improvement. With the assistance of DEA, planners will be able to make informed decisions on whether further planning is required and ensure that a plan is only accepted when the plan quality is close to the best attainable one. We apply the DEA method to 37 prostate plans using two assessment parameters: rectal generalized equivalent uniform dose (gEUD) as the input and D95 (the minimum dose that is received by 95% volume of a structure) of the planning target volume (PTV) as the output. The percentage volume of rectum overlapping PTV is used to account for anatomical variations between patients and is included in the model as a non-discretionary output variable. Five plans that are considered of lesser quality by DEA are re-optimized with the goal to further improve rectal sparing. After re-optimization, all five plans improve in rectal gEUD without clinically considerable deterioration of the PTV D95 value. For the five re-optimized plans, the rectal gEUD is reduced by an average of 1.84 Gray (Gy) with only an average reduction of 0.07 Gy in PTV D95. The results demonstrate that DEA can correctly identify plans with potential improvements in terms of the chosen input and outputs. © 2013 Institute of Physics and Engineering in Medicine. en
dc.relation.ispartofseries Physics in Medicine and Biology en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://authors.iop.org/atom/help.nsf/0/F20EC7D4A1A670AA80256F1C0053EEFF?OpenDocument http://www.sherpa.ac.uk/romeo/issn/0031-9155/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title Quality assessment for VMAT prostate radiotherapy planning based on data envelopment analysis en
dc.type Journal Article en
dc.identifier.doi 10.1088/0031-9155/58/16/5753 en
pubs.issue 16 en
pubs.begin-page 5753 en
pubs.volume 58 en
dc.description.version AM - Accepted Manuscript en
dc.identifier.pmid 23912157 en
pubs.end-page 5769 en
dc.rights.accessrights http://purl.org/eprint/accessRights/OpenAccess en
pubs.subtype Article en
pubs.elements-id 404959 en
pubs.org-id Engineering en
pubs.org-id Engineering Science en
dc.identifier.eissn 1361-6560 en
pubs.record-created-at-source-date 2013-08-03 en
pubs.dimensions-id 23912157 en

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