The crystal structures of the bromo and chloro derivatives of picrotoxinin / Bryan Maxwell Craven

Abstract

Picrotoxin is the bitter tasting convulsive poison, obtained from the cocculus berries, the fruit of the East Indian creepers, Menispermum cocculus and Anamirta paniculata. It has been used extensively in medicine as anti-barbiturate. Although picrotoxin was first isolated in 1812 by Boullay and has been the subject of exhaustive research since then, the problem of its structure is still incompletely solved.