dc.contributor.author |
Bradnam, Lynley |
en |
dc.contributor.author |
Stinear, Cathy |
en |
dc.contributor.author |
Byblow, Winston |
en |
dc.coverage.spatial |
Switzerland |
en |
dc.date.accessioned |
2015-07-16T00:11:09Z |
en |
dc.date.issued |
2013 |
en |
dc.identifier.citation |
Frontiers in Human Neuroscience, 2013, 7, Article number 184 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/26272 |
en |
dc.description.abstract |
In humans the two cerebral hemispheres have essential roles in controlling the upper limb. The purpose of this article is to draw attention to the potential importance of ipsilateral descending pathways for functional recovery after stroke, and the use of non-invasive brain stimulation (NBS) protocols of the contralesional primary motor cortex (M1). Conventionally NBS is used to suppress contralesional M1, and to attenuate transcallosal inhibition onto the ipsilesional M1. There has been little consideration of the fact that contralesional M1 suppression may also reduce excitability of ipsilateral descending pathways that may be important for paretic upper limb control for some patients. One such ipsilateral pathway is the cortico-reticulo-propriospinal pathway (CRPP). In this review we outline a neurophysiological model to explain how contralesional M1 may gain control of the paretic arm via the CRPP. We conclude that the relative importance of the CRPP for motor control in individual patients must be considered before using NBS to suppress contralesional M1. Neurophysiological, neuroimaging, and clinical assessments can assist this decision making and facilitate the translation of NBS into the clinical setting. |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
Frontiers in Human Neuroscience |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.frontiersin.org/Copyright.aspx
http://www.sherpa.ac.uk/romeo/issn/1662-5161/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.rights.uri |
http://creativecommons.org/licenses/by/4.0/ |
en |
dc.subject |
propriospinal |
en |
dc.subject |
rehabilitation |
en |
dc.subject |
stroke |
en |
dc.subject |
transcranial direct current stimulation |
en |
dc.subject |
upper limb |
en |
dc.title |
Ipsilateral motor pathways after stroke: implications for non-invasive brain stimulation |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.3389/fnhum.2013.00184 |
en |
pubs.volume |
7 |
en |
dc.description.version |
VoR - Version of Record |
en |
dc.identifier.pmid |
23658541 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Journal Article |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
379950 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Exercise Sciences |
en |
dc.identifier.eissn |
1662-5161 |
en |
pubs.number |
184 |
en |
pubs.record-created-at-source-date |
2015-07-16 |
en |
pubs.dimensions-id |
23658541 |
en |