dc.contributor.author |
Middleton, Danielle |
en |
dc.contributor.author |
Nelson, NJ |
en |
dc.contributor.author |
Gartrell, BD |
en |
dc.contributor.author |
La Flamme, AC |
en |
dc.date.accessioned |
2015-07-26T23:42:49Z |
en |
dc.date.available |
2015-06-11 |
en |
dc.date.issued |
2015-08 |
en |
dc.identifier.citation |
Comparative Immunology, Microbiology and Infectious Diseases, 2015, 41 pp. 17 - 27 |
en |
dc.identifier.issn |
0147-9571 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/26431 |
en |
dc.description.abstract |
Colonisation of a host by pathogenic microorganisms is a near constant threat to the health of all vertebrates and most species have evolved an efficient adaptive immune response which produces antibodies following exposure to a specific antigen. The strength of this response can be influenced by many factors including sex and season. Tuatara are exposed to Salmonella through contact with infected skinks and soil; however, no gastrointestinal colonisation of tuatara with Salmonella has been found. Using Western blot and flow cytometry we have demonstrated that tuatara possess antibodies which recognise Salmonella antigens, but many of these antibodies are not specific and are cross-reactive with two closely related and ubiquitous bacteria, Escherichia coli and Citrobacter koseri. Our study describes the anti-Salmonella immune responses in tuatara and will help to inform decisions around maintaining wildlife health, as well as providing important insights into the role and development of adaptive immunity in reptilian species. |
en |
dc.language |
English |
en |
dc.publisher |
Elsevier |
en |
dc.relation.ispartofseries |
Comparative Immunology, Microbiology and Infectious Diseases |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0147-9571/
http://www.journals.elsevier.com/comparative-immunology-microbiology-and-infectious-diseases/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Presence of antibodies to Salmonella in tuatara (Sphenodon punctatus) sera |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.cimid.2015.06.001 |
en |
pubs.begin-page |
17 |
en |
pubs.volume |
41 |
en |
dc.rights.holder |
Copyright:
Elsevier |
en |
pubs.author-url |
http://www.sciencedirect.com/science/article/pii/S0147957115000405 |
en |
pubs.end-page |
27 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
489222 |
en |
dc.identifier.eissn |
1878-1667 |
en |
pubs.record-created-at-source-date |
2015-07-27 |
en |