Human Adipose-Derived Stem Cells (ASC): Their efficacy in clinical applications

Show simple item record Locke, Michelle en Feisst, Vaughan en
dc.contributor.editor Bhattacharya, N en
dc.contributor.editor Stubblefield, PG en 2015-08-10T04:35:11Z en 2015 en
dc.identifier.citation In N. Bhattacharya & P. G. Stubblefield (Eds.). (2015). Regenerative Medicine Using Non-Fetal Sources of Stem Cells (pp. 135 - 149). London: Springer, en
dc.identifier.isbn 1447165411 en
dc.identifier.isbn 978-1-4471-6541-5 en
dc.identifier.uri en
dc.description.abstract Mesenchymal stem cells (MSC) have been used for therapeutic purposes for many years. Multipotent cells in adipose tissue were postulated to exist by Kaplan and colleagues during their investigations into a disease called progressive osseous heteroplasia (POH). In this disease, bone forms in atypical locations, such as in subcutaneous fat or in muscle. Interest in multilineage cells from adipose tissue gained momentum after 2001, when Zuk and her colleagues published their sentinel paper showing differentiation of stromal-type cells from adipose tissue along adipogenic, chondrogenic and osteogenic lineages. Such has been the explosion of interest in the topic, a Medline search with “adipose” and “stem” and “cell” as the key words returns nearly 3,000 articles published since this time, compared with only 300 in the 30 years prior to this. The cells isolated from adipose tissue have been given various names, including adipose stem cells, adipose-derived stem cells, adipose-derived stromal cells, among others. A consensus statement was published following the International Fat Applied Technology Society (IFATS, now known as the International Federation for Adipose Therapeutics and Science) 2nd international meeting in 2004, concluding that they should be referred to as adipose-derived stem/stromal cells (ASC) to promote consistency across research group; hence, this is the terminology used in this article en
dc.description.uri en
dc.publisher Springer-Verlag en
dc.relation.ispartof Regenerative medicine en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.title Human Adipose-Derived Stem Cells (ASC): Their efficacy in clinical applications en
dc.type Book Item en
dc.identifier.doi 10.1007/978-1-4471-6542-2 en
pubs.begin-page 135 en
dc.rights.holder Copyright: Springer-Verlag en
pubs.end-page 149 en London, UK en
dc.rights.accessrights en
pubs.elements-id 466910 en Medical and Health Sciences en School of Medicine en Surgery Department en Science en Biological Sciences en
pubs.number 13 en
pubs.record-created-at-source-date 2014-12-03 en

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