Abstract:
Although the value of DNA profiles found at a crime scene is indisputable, there is increasing importance in identifying the cellular source of the DNA as well as the identity of the person to whom the profile belongs. Knowledge regarding the cellular source from which the DNA profile originates increases the evidential value of the sample. Our research involves investigation of protein candidates in order to find an epithelial cell type-specific protein that will enable differentiation of vaginal, buccal and skin cells in forensic samples. We have used several methods including histochemical stains, western analysis and immunohistochemistry to investigate candidate proteins known to be present in various types of epithelial cells. Our most current results from these studies will be presented here.
