dc.contributor.author |
Barber, Peter |
en |
dc.contributor.author |
Pridmore, HM |
en |
dc.contributor.author |
Krishnamurthy, V |
en |
dc.contributor.author |
Roberts, S |
en |
dc.contributor.author |
Spriggs, DA |
en |
dc.contributor.author |
Carter, KN |
en |
dc.contributor.author |
Anderson, NE |
en |
dc.date.accessioned |
2016-06-27T03:49:29Z |
en |
dc.date.issued |
2013-08 |
en |
dc.identifier.citation |
Stroke, 2013, 44 (8), pp. 2327 - 2329 |
en |
dc.identifier.issn |
0039-2499 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/29195 |
en |
dc.description.abstract |
Background and Purpose—There is a temporal relationship between cannabis use and stroke in case series and population-based studies. Methods—Consecutive stroke patients, aged 18 to 55 years, who had urine screens for cannabis were compared with a cohort of control patients admitted to hospital without cardiovascular or neurological diagnoses. Results—One hundred sixty of 218 (73%) ischemic stroke/transient ischemic attack patients had urine drug screens (100 men; mean [SD] age, 44.8 [8.7] years). Twenty-five (15.6%) patients had positive cannabis drug screens. These patients were more likely to be men (84% versus 59%; χ2: P=0.016) and tobacco smokers (88% versus 28%; χ2: P<0.001). Control urine samples were obtained from 160 patients matched for age, sex, and ethnicity. Thirteen (8.1%) control participants tested positive for cannabis. In a logistic regression analysis adjusted for age, sex, and ethnicity, cannabis use was associated with increased risk of ischemic stroke/transient ischemic attack (odds ratio, 2.30; 95% confidence interval, 1.08–5.08). However after adjusting for tobacco use, an association independent of tobacco could not be confirmed (odds ratio, 1.59; 95% confidence interval, 0.71–3.70). Conclusions—This study provides evidence of an association between a cannabis lifestyle that includes tobacco and ischemic stroke. Further research is required to clarify whether there is an association between cannabis and stroke independent of tobacco. |
en |
dc.description.uri |
http://stroke.ahajournals.org/ |
en |
dc.publisher |
American Heart Association |
en |
dc.relation.ispartofseries |
Stroke |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0039-2499/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
cannabis |
en |
dc.subject |
drug abuse |
en |
dc.subject |
ischemic stroke |
en |
dc.subject |
transient ischemic attack |
en |
dc.subject |
Adolescent |
en |
dc.subject |
Adult |
en |
dc.subject |
Brain Ischemia |
en |
dc.subject |
Cannabis |
en |
dc.subject |
Case-Control Studies |
en |
dc.subject |
Cohort Studies |
en |
dc.subject |
Comorbidity |
en |
dc.subject |
Female |
en |
dc.subject |
Humans |
en |
dc.subject |
Ischemic Attack, Transient |
en |
dc.subject |
Male |
en |
dc.subject |
Middle Aged |
en |
dc.subject |
New Zealand |
en |
dc.subject |
Stroke |
en |
dc.subject |
Substance-Related Disorders |
en |
dc.subject |
Tobacco |
en |
dc.subject |
Young Adult |
en |
dc.title |
Cannabis, Ischemic Stroke, and Transient Ischemic Attack: A Case-Control Study |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1161/STROKEAHA.113.001562 |
en |
pubs.issue |
8 |
en |
pubs.begin-page |
2327 |
en |
pubs.volume |
44 |
en |
dc.rights.holder |
Copyright:
American Heart Association |
en |
dc.identifier.pmid |
23696547 |
en |
pubs.author-url |
http://stroke.ahajournals.org/content/44/8/2327.full |
en |
pubs.end-page |
2329 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
375354 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
dc.identifier.eissn |
1524-4628 |
en |
dc.identifier.pii |
STROKEAHA.113.001562 |
en |
pubs.record-created-at-source-date |
2016-06-27 |
en |
pubs.dimensions-id |
23696547 |
en |