dc.contributor.author |
Ackerley, Suzanne |
en |
dc.contributor.author |
Stinear, Cathy |
en |
dc.contributor.author |
Barber, Peter |
en |
dc.contributor.author |
Byblow, Winston |
en |
dc.date.accessioned |
2016-07-11T22:34:57Z |
en |
dc.date.issued |
2014-07 |
en |
dc.identifier.citation |
Clinical Neurophysiology, 2014, 125 (7), pp. 1451 - 1458 |
en |
dc.identifier.issn |
1388-2457 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/29374 |
en |
dc.description.abstract |
Objective This double-blind sham-controlled crossover study investigated the interactions between primary sensory and motor cortex after stroke and their response to Theta Burst Stimulation (TBS). Methods Thirteen chronic subcortical stroke patients with upper limb impairment performed standardised dexterity training primed with ipsilesional M1 intermittent TBS (iTBSiM1), contralesional M1 continuous TBS (cTBScM1) or sham TBS. The effects on sensorimotor integration, corticomotor excitability, sensation and grip-lift kinetics were examined. Results After iTBSiM1, improvements in paretic grip-lift performance were accompanied by an immediate facilitation of ipsilesional M1 excitability and a subsequent increase in ipsilesional short latency afferent inhibition (SAI) during training. Precision grip-lift performance improved after cTBScM1 and training, alongside increased ipsilesional M1 excitability with no effect on ipsilesional SAI. There were no effects on sensory performance. Conclusion Primary motor cortex iTBS not only modulates M1 corticospinal excitability but also increases M1 receptiveness to sensory input. Significance Priming with iTBSiM1 may enhance ipsilesional sensorimotor integration and facilitate better quality sensorimotor training after subcortical stroke. |
en |
dc.relation.ispartofseries |
Clinical Neurophysiology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Priming sensorimotor cortex to enhance task-specific training after subcortical stroke |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.clinph.2013.11.020 |
en |
pubs.issue |
7 |
en |
pubs.begin-page |
1451 |
en |
pubs.volume |
125 |
en |
dc.identifier.pmid |
24360934 |
en |
pubs.author-url |
http://www.clinph-journal.com/article/S1388-2457(13)01217-0/abstract |
en |
pubs.end-page |
1458 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
272804 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Exercise Sciences |
en |
dc.identifier.eissn |
1872-8952 |
en |
pubs.record-created-at-source-date |
2014-12-08 |
en |
pubs.dimensions-id |
24360934 |
en |