dc.contributor.author |
Egbert, Matthew |
en |
dc.contributor.editor |
Dalby, AR |
en |
dc.date.accessioned |
2016-08-26T04:51:28Z |
en |
dc.date.available |
2013-04-04 |
en |
dc.date.issued |
2013-05-22 |
en |
dc.identifier.citation |
PLoS ONE, 2013, 8 (5), e63617 |
en |
dc.identifier.issn |
1932-6203 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/30159 |
en |
dc.description.abstract |
Using a minimal model of metabolism, we examine the limitations of behavior that is (a) solely in response to environmental phenomena or (b) solely in response to metabolic dynamics, showing that basic forms of each of these kinds of behavior are incapable of driving survival-prolonging behavior in certain situations. Inspired by experimental evidence of concurrent metabolism-based and metabolism-independent chemotactic mechanisms in Escherichia coli and Rhodobacter sphaeroides, we then investigate how metabolism-independent and metabolism-based sensitivities can be integrated into a single behavioral response, demonstrating that a simple switching mechanism can be sufficient to effectively integrate metabolism-based and metabolism-independent behaviors. Finally, we use a spatial simulation of bacteria to show that the investigated forms of behavior produce different spatio-temporal patterns that are influenced by the metabolic-history of the bacteria. We suggest that these patterns could be a way to experimentally derive insight into the relationship between metabolism and chemotaxis in real bacteria. |
en |
dc.language |
English |
en |
dc.publisher |
Public Library of Science |
en |
dc.relation.ispartofseries |
PLoS ONE |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1932-6203/
https://www.plos.org/editorial-publishing-policies |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.rights.uri |
https://creativecommons.org/licenses/by/3.0/ |
en |
dc.title |
Bacterial Chemotaxis: Introverted or Extroverted? A Comparison of the Advantages and Disadvantages of Basic Forms of Metabolism-Based and Metabolism-Independent Behavior Using a Computational Model |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1371/journal.pone.0063617 |
en |
pubs.issue |
5 |
en |
pubs.volume |
8 |
en |
dc.description.version |
VoR - Version of Record |
en |
pubs.author-url |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063617 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
537918 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
School of Computer Science |
en |
dc.identifier.eissn |
1932-6203 |
en |
pubs.number |
e63617 |
en |
pubs.record-created-at-source-date |
2016-08-26 |
en |
pubs.online-publication-date |
2013-05-22 |
en |