dc.contributor.author |
Askarian Amiri, Effat |
en |
dc.contributor.author |
Leung, Yee Fun |
en |
dc.contributor.author |
Finlay, Graeme |
en |
dc.contributor.author |
Baguley, Bruce |
en |
dc.contributor.editor |
Reuff, J |
en |
dc.contributor.editor |
Rodrigues, AS |
en |
dc.date.accessioned |
2016-09-09T04:17:49Z |
en |
dc.date.issued |
2016 |
en |
dc.identifier.citation |
In Cancer drug resistance: Overviews and methods. Editors: Reuff J, Rodrigues AS. 1395: 207-277. Humana Press / Springer, New York, NY 2016 |
en |
dc.identifier.isbn |
1493933450 |
en |
dc.identifier.isbn |
9781493933471 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/30291 |
en |
dc.description.abstract |
Recent genomic and transcriptomic analysis has revealed that the majority of the human genome is transcribed as nonprotein-coding RNA. These transcripts, known as long noncoding RNA, have structures similar to those of mRNA. Many of these transcripts are now thought to have regulatory roles in different biological pathways which provide cells with an additional layer of regulatory complexity in gene expression and proteome function in response to stimuli. A wide variety of cellular functions may thus depend on the fine-tuning of interactions between noncoding RNAs and other key molecules in cell signaling networks. Deregulation of many noncoding RNAs is thought to occur in a variety of human diseases, including neoplasia and cancer drug resistance. Here we discuss recent findings on the molecular functions of long noncoding RNAs in cellular pathways mediating resistance to anticancer drugs. |
en |
dc.description.uri |
http://librarysearch.auckland.ac.nz/UOA2_A:Combined_Local:uoa_alma51256364540002091 |
en |
dc.publisher |
Humana Press / Springer |
en |
dc.relation.ispartof |
Cancer drug resistance: Overviews and methods |
en |
dc.relation.ispartofseries |
Methods in molecular biology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
The regulatory role of long noncoding RNAs in cancer drug resistance |
en |
dc.type |
Book Item |
en |
dc.identifier.doi |
10.1007/978-1-4939-3347-1_12 |
en |
pubs.begin-page |
207 |
en |
pubs.volume |
1395 |
en |
dc.rights.holder |
Copyright:
Humana Press / Springer |
en |
dc.identifier.pmid |
26910076 |
en |
pubs.author-url |
https://books.google.co.nz/books?id=g8ACswEACAAJ |
en |
pubs.end-page |
277 |
en |
pubs.place-of-publication |
New York, NY |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.elements-id |
492428 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Auckland Cancer Research |
en |
pubs.org-id |
Molecular Medicine |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
pubs.number |
12 |
en |
pubs.record-created-at-source-date |
2015-07-29 |
en |
pubs.dimensions-id |
26910076 |
en |