Prospective surveillance of hospitalisations associated with varicella in New Zealand children

Show simple item record Wen, SC-H en Best, Emma en Walls, T en Dickson, N en McCay, H en Wilson, E en 2016-09-13T00:02:27Z en 2015-11 en
dc.identifier.citation Journal of Paediatrics and Child Health, 2015, 51 (11), pp. 1078 - 1083 en
dc.identifier.issn 1034-4810 en
dc.identifier.uri en
dc.description.abstract Aim: Varicella is a vaccine-preventable disease not notifiable in New Zealand (NZ), and varicella vaccine is not funded in the National Immunisation Schedule (NIS). Hospitalisations can occur because of bacterial secondary infection and other complications, which can result in long-term sequelae. Varicella may not be acknowledged in discharge coding when complications occur weeks after infection. Using the New Zealand Paediatric Surveillance Unit (NZPSU), the aim of this study was to document the hospitalisation burden of this disease. Methods: Cases (0–14years) of varicella and post-varicella complications requiring hospitalisation, including stroke syndromes where varicella occurred in the preceding 6 months, were notified to NZPSU between 1 November 2011 and 31 October 2013. Herpes zoster cases were excluded. Questionnaires were used to capture demographics, clinical features, management and short-term outcomes. Results: One hundred seventy-eight notifications were received and 144 were confirmed cases. Overall incidence was 8.3/100 000 children per year. Fifty-two per cent were women with a median age of 2.4 years. Māori and Pacific Island (PI) children accounted for 74% of hospitalisations, with incidence rate ratios compared with European children of 2.8 and 3.9, respectively (P < 0.01). Complications included: infection (75%), respiratory (11%), neurological (11%), electrolyte disturbance (6%) and haemorrhagic varicella (4%). Nine per cent were immunocompromised. Median duration of hospital admission was 4 days with 9% requiring intensive care admission. There were no reported deaths; however, 19% had ongoing problems at discharge. Conclusion: Varicella has more associated morbidity than commonly perceived in immunocompetent children. Māori and PI children are more likely to have complications. This surveillance gives support for inclusion of universal varicella vaccine in the NZ NIS. en
dc.description.uri en
dc.publisher Wiley en
dc.relation.ispartofseries Journal of Paediatrics and Child Health en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.title Prospective surveillance of hospitalisations associated with varicella in New Zealand children en
dc.type Journal Article en
dc.identifier.doi 10.1111/jpc.12937 en
pubs.issue 11 en
pubs.begin-page 1078 en
pubs.volume 51 en
dc.rights.holder Copyright: The Authors. Paediatrics and Child Health Division (Royal Australasian College of Physicians) en
dc.identifier.pmid 26041441 en en
pubs.end-page 1083 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 488651 en Medical and Health Sciences en School of Medicine en Paediatrics Child & Youth Hlth en
dc.identifier.eissn 1440-1754 en
pubs.record-created-at-source-date 2016-09-13 en
pubs.dimensions-id 26041441 en

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