Synthesis of Alocasin A

Kim, Se Hun; Sperry, Jonathan

dc.contributor.author	Kim, Se Hun	en
dc.contributor.author	Sperry, Jonathan	en
dc.date.accessioned	2016-11-04T02:26:19Z	en
dc.date.issued	2015	en
dc.identifier.citation	Journal of Natural Products, 2015, 78(12), pp. 3080-3082	en
dc.identifier.issn	0163-3864	en
dc.identifier.uri	http://hdl.handle.net/2292/30964	en
dc.description.abstract	Herein is reported a synthesis of alocasin A (1), an alkaloid component of Alocasia macrorrhiza, a herbaceous plant used in folk medicine throughout southern Asia. A double Suzuki-Miyaura cross-coupling reaction between a 3-borylindole and 2,5-dibromopyrazine was used to assemble the heteroaromatic framework of the natural product. Removal of the protecting groups gave a synthetic sample of 1, the spectroscopic data of which matched those in the isolation report of this compound.	en
dc.description.uri	http://pubs.acs.org/journal/jnprdf	en
dc.publisher	American Chemical Society	en
dc.relation.ispartofseries	Journal of Natural Products	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0163-3864/	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.subject	Alocasia	en
dc.subject	Alkaloids	en
dc.subject	Biological Products	en
dc.subject	Medicine, Traditional	en
dc.subject	Molecular Structure	en
dc.title	Synthesis of Alocasin A	en
dc.type	Journal Article	en
dc.identifier.doi	10.1021/acs.jnatprod.5b00853	en
pubs.issue	12	en
pubs.begin-page	3080	en
pubs.volume	78	en
dc.rights.holder	Copyright: American Chemical Society	en
dc.identifier.pmid	26625266	en
pubs.author-url	http://pubs.acs.org/doi/abs/10.1021/acs.jnatprod.5b00853	en
pubs.end-page	3082	en
pubs.publication-status	Published	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	512738	en
pubs.org-id	Science	en
pubs.org-id	Chemistry	en
dc.identifier.eissn	1520-6025	en
pubs.record-created-at-source-date	2016-11-04	en
pubs.dimensions-id	26625266	en