Synthesis of Alocasin A

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Show simple item record Kim, Se Hun en Sperry, Jonathan en 2016-11-04T02:26:19Z en 2015 en
dc.identifier.citation Journal of Natural Products, 2015, 78(12), pp. 3080-3082 en
dc.identifier.issn 0163-3864 en
dc.identifier.uri en
dc.description.abstract Herein is reported a synthesis of alocasin A (1), an alkaloid component of Alocasia macrorrhiza, a herbaceous plant used in folk medicine throughout southern Asia. A double Suzuki-Miyaura cross-coupling reaction between a 3-borylindole and 2,5-dibromopyrazine was used to assemble the heteroaromatic framework of the natural product. Removal of the protecting groups gave a synthetic sample of 1, the spectroscopic data of which matched those in the isolation report of this compound. en
dc.description.uri en
dc.publisher American Chemical Society en
dc.relation.ispartofseries Journal of Natural Products en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.subject Alocasia en
dc.subject Alkaloids en
dc.subject Biological Products en
dc.subject Medicine, Traditional en
dc.subject Molecular Structure en
dc.title Synthesis of Alocasin A en
dc.type Journal Article en
dc.identifier.doi 10.1021/acs.jnatprod.5b00853 en
pubs.issue 12 en
pubs.begin-page 3080 en
pubs.volume 78 en
dc.rights.holder Copyright: American Chemical Society en
dc.identifier.pmid 26625266 en en
pubs.end-page 3082 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 512738 en Science en Chemistry en
dc.identifier.eissn 1520-6025 en
pubs.record-created-at-source-date 2016-11-04 en
pubs.dimensions-id 26625266 en

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