dc.contributor.author |
Muhlhausler, BS |
en |
dc.contributor.author |
Hancock, SN |
en |
dc.contributor.author |
Bloomfield, Francis |
en |
dc.contributor.author |
Harding, R |
en |
dc.coverage.spatial |
United States |
en |
dc.date.accessioned |
2016-11-21T01:38:02Z |
en |
dc.date.available |
2011-02-24 |
en |
dc.date.issued |
2011-08 |
en |
dc.identifier.citation |
Pediatric Research, Aug 2011, 70 (2), 117 - 122 |
en |
dc.identifier.issn |
0031-3998 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/31106 |
en |
dc.description.abstract |
It is now well established that IUGR is associated with an increased risk of a range of adult onset diseases, including cardiovascular disease, obesity, and type 2 diabetes. Infants from twin pregnancies are generally born smaller than singletons; therefore, it has been suggested that twins represent a naturally occurring model of IUGR. Although twin gestations contribute significantly to the population burden of preterm birth and small size at birth, whether twins have the same long-term health consequences as IUGR singletons remains unclear. The purpose of this review is to consider what is currently known about the clinical implications of twinning, the differences that exist between the growth and developmental profiles of singleton and twin fetuses, and to use this as a basis for exploring the question of whether fetuses conceived as twins are analogous to IUGR singletons of similar birthweight and gestation. This question is increasingly important in both the clinical and research settings, because the incidence of twinning is increasing and the long-term implications of reduced size at birth are mostly investigated in species which bear multiple offspring. |
en |
dc.description.uri |
https://www.ncbi.nlm.nih.gov/labs/articles/21505376/ |
en |
dc.language |
English |
en |
dc.relation.ispartofseries |
Pediatric Research |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/0031-3998/
http://www.nature.com/authors/policies/license.html |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Birth Weight |
en |
dc.subject |
Developed Countries |
en |
dc.subject |
Female |
en |
dc.subject |
Fetal Development |
en |
dc.subject |
Fetal Growth Retardation |
en |
dc.subject |
Growth |
en |
dc.subject |
Humans |
en |
dc.subject |
Perinatal Mortality |
en |
dc.subject |
Pregnancy |
en |
dc.subject |
Pregnancy Outcome |
en |
dc.subject |
Twins |
en |
dc.title |
Are twins growth restricted? |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1203/PDR.0b013e31821f6cfd |
en |
pubs.issue |
2 |
en |
pubs.begin-page |
117 |
en |
pubs.volume |
70 |
en |
dc.description.version |
VoR - Version of Record |
en |
dc.identifier.pmid |
21505376 |
en |
pubs.author-url |
http://www.nature.com/pr/journal/v70/n2/abs/pr2011143a.html |
en |
pubs.end-page |
122 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Review |
en |
pubs.elements-id |
209345 |
en |
pubs.org-id |
Liggins Institute |
en |
pubs.org-id |
LiFePATH |
en |
dc.identifier.eissn |
1530-0447 |
en |
pubs.record-created-at-source-date |
2016-11-21 |
en |
pubs.dimensions-id |
21505376 |
en |