Are twins growth restricted?

Show simple item record Muhlhausler, BS en Hancock, SN en Bloomfield, Francis en Harding, R en
dc.coverage.spatial United States en 2016-11-21T01:38:02Z en 2011-02-24 en 2011-08 en
dc.identifier.citation Pediatric Research, Aug 2011, 70 (2), 117 - 122 en
dc.identifier.issn 0031-3998 en
dc.identifier.uri en
dc.description.abstract It is now well established that IUGR is associated with an increased risk of a range of adult onset diseases, including cardiovascular disease, obesity, and type 2 diabetes. Infants from twin pregnancies are generally born smaller than singletons; therefore, it has been suggested that twins represent a naturally occurring model of IUGR. Although twin gestations contribute significantly to the population burden of preterm birth and small size at birth, whether twins have the same long-term health consequences as IUGR singletons remains unclear. The purpose of this review is to consider what is currently known about the clinical implications of twinning, the differences that exist between the growth and developmental profiles of singleton and twin fetuses, and to use this as a basis for exploring the question of whether fetuses conceived as twins are analogous to IUGR singletons of similar birthweight and gestation. This question is increasingly important in both the clinical and research settings, because the incidence of twinning is increasing and the long-term implications of reduced size at birth are mostly investigated in species which bear multiple offspring. en
dc.description.uri en
dc.language English en
dc.relation.ispartofseries Pediatric Research en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.subject Birth Weight en
dc.subject Developed Countries en
dc.subject Female en
dc.subject Fetal Development en
dc.subject Fetal Growth Retardation en
dc.subject Growth en
dc.subject Humans en
dc.subject Perinatal Mortality en
dc.subject Pregnancy en
dc.subject Pregnancy Outcome en
dc.subject Twins en
dc.title Are twins growth restricted? en
dc.type Journal Article en
dc.identifier.doi 10.1203/PDR.0b013e31821f6cfd en
pubs.issue 2 en
pubs.begin-page 117 en
pubs.volume 70 en
dc.description.version VoR - Version of Record en
dc.identifier.pmid 21505376 en en
pubs.end-page 122 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype Review en
pubs.elements-id 209345 en Liggins Institute en LiFePATH en
dc.identifier.eissn 1530-0447 en
pubs.record-created-at-source-date 2016-11-21 en
pubs.dimensions-id 21505376 en

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