Factors associated with medication adherence in school-aged children with asthma

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dc.contributor.author Chan, Amy en
dc.contributor.author Stewart, Alistair en
dc.contributor.author Foster, JM en
dc.contributor.author Mitchell, Edwin en
dc.contributor.author Camargo, Carlos en
dc.contributor.author Harrison, Jeffrey en
dc.date.accessioned 2016-11-30T03:34:43Z en
dc.date.available 2016-02-28 en
dc.date.issued 2016-03-30 en
dc.identifier.citation ERJ Open Research, 30 March 2016, 2 (1), Article 00087-2015-87-2015 en
dc.identifier.uri http://hdl.handle.net/2292/31198 en
dc.description.abstract Adherence to preventive asthma treatment is poor, particularly in children, yet the factors associated with adherence in this age group are not well understood. Adherence was monitored electronically over 6 months in school-aged children who attended a regional emergency department in New Zealand for an asthma exacerbation and were prescribed twice-daily inhaled corticosteroids. Participants completed questionnaires including assessment of family demographics, asthma responsibility and learning style. Multivariable analysis of factors associated with adherence was conducted. 101 children (mean (range) age 8.9 (6–15) years, 51% male) participated. Median (interquartile range) preventer adherence was 30% (17–48%) of prescribed. Four explanatory factors were identified: female sex (+12% adherence), Asian ethnicity (+19% adherence), living in a smaller household (−3.0% adherence per person in the household), and younger age at diagnosis (+2.7% for every younger year of diagnosis) (all p<0.02). In school-aged children attending the emergency department for asthma, males and non-Asian ethnic groups were at high risk for poor inhaled corticosteroid adherence and may benefit most from intervention. Four factors explained a small proportion of adherence behaviour indicating the difficulty in identifying adherence barriers. Further research is recommended in other similar populations. en
dc.description.uri https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005164/ en
dc.language English en
dc.publisher ERS Publications en
dc.relation.ispartofseries ERJ Open Research en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.rights.uri https://creativecommons.org/licenses/by-nc/4.0/ en
dc.title Factors associated with medication adherence in school-aged children with asthma en
dc.type Journal Article en
dc.identifier.doi 10.1183/23120541.00087-2015 en
pubs.issue 1 en
pubs.volume 2 en
dc.description.version VoR - Version of Record en
dc.identifier.pmid 27730181 en
pubs.author-url http://openres.ersjournals.com/content/2/1/00087-2015 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/OpenAccess en
pubs.subtype Article en
pubs.elements-id 539149 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Pharmacy en
pubs.org-id School of Medicine en
pubs.org-id Paediatrics Child & Youth Hlth en
dc.identifier.eissn 2312-0541 en
pubs.number 00087-2015 en
pubs.record-created-at-source-date 2016-11-30 en
pubs.online-publication-date 2016-03-30 en
pubs.dimensions-id 27730181 en


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