The Influence of prostaglandins and other agents on the resorption and synthesis of mouse calvarial bone in culture

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dc.contributor.advisor Gray, D.H en
dc.contributor.advisor Skunner, S.J.M. en
dc.contributor.author Katz, June Margaret en
dc.date.accessioned 2008-10-29T01:16:42Z en
dc.date.available 2008-10-29T01:16:42Z en
dc.date.issued 1983 en
dc.identifier.citation Thesis (PhD--Surgery)--University of Auckland, 1983 en
dc.identifier.uri http://hdl.handle.net/2292/3125 en
dc.description Restricted Item. Print thesis available in the University of Auckland Library or may be available through Interlibrary Loan. en
dc.description.abstract Calvaria dissected from 6-day-old mice were maintained in organ culture in a chemically-defined medium without serum additives. Bone resorption was quantified by the release of 45Ca or hydroxyproline (Hyp) into the medium. Collagen synthesis (Hyp) in bone was estimated by the incorporation of [5-3H]-proline. Prostaglandin E2 (PGE2), prostaglandin F (PGF) and 6-keto-prostaglandin F1a (6-keto-PGF1a) released into the medium from cultured calvaria, were measured by radioimmunoassay. Prostanoids were also quantified by the release of radioactively-labelled metabolites from calvaria pre-labelled in vitro with [3H]-arachidonic acid. These metabolites were separated by high performance liquid chromatography. en
dc.language.iso en en
dc.publisher ResearchSpace@Auckland en
dc.relation.ispartof PhD Thesis - University of Auckland en
dc.relation.isreferencedby UoA9977688814002091 en
dc.rights Restricted Item. Print thesis available in the University of Auckland Library or may be available through Interlibrary Loan. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title The Influence of prostaglandins and other agents on the resorption and synthesis of mouse calvarial bone in culture en
dc.type Thesis en
thesis.degree.discipline Surgery en
thesis.degree.grantor The University of Auckland en
thesis.degree.level Doctoral en
thesis.degree.name PhD en
dc.subject.marsden Fields of Research::320000 Medical and Health Sciences::321000 Clinical Sciences::321029 Surgery en
dc.rights.holder Copyright: The author en
dc.rights.accessrights http://purl.org/eprint/accessRights/ClosedAccess en
dc.identifier.wikidata Q112847390


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