dc.contributor.author |
Stamp, L |
en |
dc.contributor.author |
Dalbeth, Nicola |
en |
dc.date.accessioned |
2017-03-03T00:38:11Z |
en |
dc.date.issued |
2017-02 |
en |
dc.identifier.citation |
Seminars in Arthritis and Rheumatism 46(4):457-464 Feb 2017 |
en |
dc.identifier.issn |
0049-0172 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/32039 |
en |
dc.description.abstract |
Objective The observed associations of hyperuricaemia with hypertension, cardiovascular disease and kidney disease are receiving increasing interest. The potential role of urate-lowering therapy in the management of these “non-gout diseases” has been raised, and in some countries it is already recommended. However, there is no consistent definition of hyperuricaemia or asymptomatic hyperuricaemia, much remains unknown about the causal role of urate in these “non-gout diseases” and there is currently a lack of evidence about the effects of urate lowering on disease progression. In addition, there is potential for serious adverse effects associated with urate-lowering therapies with recent evidence suggesting that asymptomatic hyperuricaemia may be an independent risk factor for the potentially fatal allopurinol hypersensitivity syndrome. Methods Pubmed was searched in January 2016 using the search term “asymptomatic hyperuricaemia”. Results and Conclusions Herein, we discuss the issues related to treating asymptomatic hyperuricaemia, which at present seems premature. |
en |
dc.publisher |
Elsevier |
en |
dc.relation.ispartofseries |
Seminars in Arthritis and Rheumatism |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Urate-lowering therapy for asymptomatic hyperuricaemia: A need for caution |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.semarthrit.2016.07.015 |
en |
pubs.issue |
4 |
en |
pubs.begin-page |
457 |
en |
pubs.volume |
46 |
en |
dc.rights.holder |
Copyright: Elsevier |
en |
dc.identifier.pmid |
27591828 |
en |
pubs.end-page |
464 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
541262 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
dc.identifier.eissn |
1532-866X |
en |
pubs.record-created-at-source-date |
2017-03-03 |
en |
pubs.online-publication-date |
2016-07 |
en |
pubs.dimensions-id |
27591828 |
en |