dc.contributor.author |
Robertson, Julia |
en |
dc.contributor.author |
Dalton, J |
en |
dc.contributor.author |
Wiles, Siouxsie |
en |
dc.contributor.author |
Gizdavic Nikolaidis, Marija |
en |
dc.contributor.author |
Swift, Simon |
en |
dc.date.accessioned |
2017-04-20T03:19:36Z |
en |
dc.date.issued |
2016-12 |
en |
dc.identifier.citation |
PeerJ 4:15 pages Article number e2795 Dec 2016 |
en |
dc.identifier.issn |
2167-8359 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/32608 |
en |
dc.description.abstract |
Tuberculosis is considered a leading cause of death worldwide. More than 95% of cases and deaths occur in low- and middle-income countries. In resource-limited countries, hospitals often lack adequate facilities to manage and isolate patients with infectious tuberculosis (TB), relying instead on personal protective equipment, such as facemasks, to reduce nosocomial transmission of the disease. Facemasks impregnated with an antimicrobial agent may be a cost-effective way of adding an extra level of protection against the spread of TB by reducing the risk of disease transmission. Conducting polymers, such as polyaniline (PANI), and their functionalised derivatives are a novel class of antimicrobial agents with potential as non-leaching additives to provide contamination resistant surfaces. We have investigated the antimicrobial action of PANI and a functionalised derivative, poly-3-aminobenzoic acid (P3ABA), against mycobacteria and have determined the optimal treatment time and concentration to achieve significant knockdown of Mycobacterium smegmatis and Mycobacterium tuberculosis on an agar surface. Results indicated that P3ABA is a potential candidate for use as an anti-tuberculoid agent in facemasks to reduce TB transmission. |
en |
dc.publisher |
PeerJ Inc. |
en |
dc.relation.ispartofseries |
PeerJ |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/2167-8359/ |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.rights.uri |
http://creativecommons.org/licenses/by/4.0/ |
en |
dc.title |
The tuberculocidal activity of polyaniline and functionalised polyanilines |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.7717/peerj.2795 |
en |
pubs.volume |
4 |
en |
dc.description.version |
AM - Accepted Manuscript |
en |
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
28028468 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
605516 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Molecular Medicine |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
dc.identifier.eissn |
2167-8359 |
en |
pubs.number |
e2795 |
en |
pubs.record-created-at-source-date |
2017-04-20 |
en |
pubs.online-publication-date |
2016-12-20 |
en |
pubs.dimensions-id |
28028468 |
en |