Atypical white matter microstructure in left-handed individuals

Show simple item record Mckay, Nicole en Iwabuchi, SJ en Häberling, IS en Corballis, Michael en Kirk, Ian en 2017-06-07T04:50:13Z en 2017-05 en
dc.identifier.citation Laterality 22(3):257-267 May 2017 en
dc.identifier.issn 1357-650X en
dc.identifier.uri en
dc.description.abstract Information regarding anatomical connectivity in the human brain can be gathered using diffusion tensor imaging (DTI). Fractional anisotropy (FA) is the most commonly derived value, and reflects how strongly directional are the underlying tracts. Differences in FA are thus associated with differences in the underlying microstructure of the brain. The relationships between these differences in microstructure and functional differences in corresponding regions have also been examined. Previous studies have found an effect of handedness on functional lateralization in the brain and corresponding microstructural differences. Here, using tract-based spatial statistics to analyse DTI-derived FA values, we further investigated the structural white matter architecture in the brains of right- and left-handed males. We found significantly higher FA values for left-handed, relatively to right-handed, individuals, in all major lobes, and in the corpus callosum. In support of previous suggestions, we find that there is a difference in the microstructure of white matter in left- and right-handed males that could underpin reduced lateralization of function in left-handed individuals. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.publisher Taylor & Francis en
dc.relation.ispartofseries Laterality en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri en
dc.subject Brain en
dc.subject Neural Pathways en
dc.subject Humans en
dc.subject Image Processing, Computer-Assisted en
dc.subject Adult en
dc.subject Male en
dc.subject Functional Laterality en
dc.subject Young Adult en
dc.subject Diffusion Tensor Imaging en
dc.subject White Matter en
dc.title Atypical white matter microstructure in left-handed individuals en
dc.type Journal Article en
dc.identifier.doi 10.1080/1357650x.2016.1175469 en
pubs.issue 3 en
pubs.begin-page 257 en
pubs.volume 22 en
dc.rights.holder Copyright: Taylor & Francis en
dc.identifier.pmid 27119972 en
pubs.end-page 267 en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 526963 en Science en Psychology en
dc.identifier.eissn 1464-0678 en
pubs.record-created-at-source-date 2017-06-07 en
pubs.dimensions-id 27119972 en

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