dc.contributor.author |
Park, Young Eun |
en |
dc.contributor.author |
Musson, David |
en |
dc.contributor.author |
Naot, Dorit |
en |
dc.contributor.author |
Cornish, Jillian |
en |
dc.date.accessioned |
2017-07-31T04:13:28Z |
en |
dc.date.issued |
2017-06 |
en |
dc.identifier.citation |
Current Opinion in Pharmacology 34:21-35 Jun 2017 |
en |
dc.identifier.issn |
1471-4892 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/34625 |
en |
dc.description.abstract |
Cell-cell communication plays a crucial role in bone development and maintenance, in health and disease. Our knowledge of the signalling pathways that regulate the communication of osteoblasts, osteoclasts and osteocytes is improving with time, giving us a better understanding of the regulation of the bone remodelling process. Bone cell communication has wider significance than the local tissue environment, however, with bone derived factors playing a role in whole-body homeostasis, including energy metabolism and kidney function. Similarly, there are a range of systemic conditions which affect the maintenance of bone mass. Understanding these complex interactions, the autocrine, paracrine and endocrine signalling involved in the regulation of bone health is paramount to a better understanding of bone disease, and ultimately developing targets for pharmaceutical intervention. |
en |
dc.format.medium |
Print-Electronic |
en |
dc.language |
eng |
en |
dc.publisher |
Elsevier BV |
en |
dc.relation.ispartofseries |
Current Opinion in Pharmacology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Cell-cell communication in bone development and whole-body homeostasis and pharmacological avenues for bone disorders |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.coph.2017.04.001 |
en |
pubs.begin-page |
21 |
en |
pubs.volume |
34 |
en |
dc.rights.holder |
Copyright: Elsevier BV |
en |
dc.identifier.pmid |
28472742 |
en |
pubs.end-page |
35 |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Review |
en |
pubs.elements-id |
624947 |
en |
pubs.org-id |
Academic Services |
en |
pubs.org-id |
Examinations |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
dc.identifier.eissn |
1471-4973 |
en |
pubs.record-created-at-source-date |
2017-07-31 |
en |
pubs.dimensions-id |
28472742 |
en |