dc.contributor.author |
Zhang, Y |
en |
dc.contributor.author |
Munir, Muhammad |
en |
dc.contributor.author |
Yu, Wei |
en |
dc.contributor.author |
Young, Brent |
en |
dc.date.accessioned |
2017-08-02T04:18:26Z |
en |
dc.date.issued |
2016-12 |
en |
dc.identifier.citation |
Korean Journal of Chemical Engineering 33(12):3343-3349 Dec 2016 |
en |
dc.identifier.issn |
0256-1115 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/34703 |
en |
dc.description.abstract |
Process models are increasingly becoming necessary for process understanding and optimizing. However, in the field of bioprocessing, modelling using a generic process simulator suffers from shortcomings given that many simulators cannot model batch mode bioreactors with varying reaction rates based on microbial metabolism. Bioprocesses, mostly batch, are difficult to model because most of the available unit operations in process simulators operate continuously. Our aim is to provide a general simulation platform to model these batch bioprocesses in commercial process simulators and explain how to transform batch processes with varying reaction rate into continuous unit operations for simulation purposes. Two typical fermentation processes, lactose fermentation and glucose/xylose co-fermentation, were simulated in steady state as case studies. The results are discussed as examples using the proposed approach. The potential of how to extend the simulation platform is also explained in detail. |
en |
dc.publisher |
Korean Institute of Chemical Engineers |
en |
dc.relation.ispartofseries |
Korean Journal of Chemical Engineering |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Modelling batch bioreactions with continuous process simulators |
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dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1007/s11814-016-0244-x |
en |
pubs.issue |
12 |
en |
pubs.begin-page |
3343 |
en |
pubs.volume |
33 |
en |
dc.rights.holder |
Copyright: Korean Institute of Chemical Engineers |
en |
pubs.end-page |
3349 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
544538 |
en |
pubs.org-id |
Engineering |
en |
pubs.org-id |
Chemical and Materials Eng |
en |
dc.identifier.eissn |
1975-7220 |
en |
pubs.record-created-at-source-date |
2017-08-02 |
en |
pubs.online-publication-date |
2016-10-13 |
en |