Comparison of Self-applied Heat Therapy for Meibomian Gland Dysfunction

Show simple item record Wang, Michael en Jaitley, Z en Lord, SM en Craig, Jennifer en 2017-08-08T04:41:51Z en 2015-09 en
dc.identifier.citation Optometry and Vision Science, 92(9):e321-e326 Sep 2015 en
dc.identifier.issn 1040-5488 en
dc.identifier.uri en
dc.description.abstract To compare the effects on ocular temperature, lipid layer grade, tear film stability, and tear meniscus height after a single application of two commercially available warm compresses in mild-to-moderate dry eye and to report participant treatment preference.Forty-one subjects with mild-to-moderate dry eye symptoms were enrolled in a randomized, paired-eye, investigator-masked trial. Heat was applied simultaneously to one eye (randomized) with a portable eye mask (EyeGiene) and to the contralateral eye with a microwave-heated flaxseed eye bag (MGDRx Eye Bag). Outer and inner eyelid temperatures, tear film lipid layer grade (LLG), and noninvasive tear film breakup time (NIBUT) were measured at baseline and immediately after 10 minutes of device application.Outer and inner eyelid temperatures, LLG, and NIBUT did not differ before treatment between eyes assigned to eye mask and eye bag therapy. All measurements were significantly increased from baseline, after warming with both devices (all p < 0.05). Outer and inner eyelid temperature changes were significantly greater with the eye bag than with the eye mask (outer eyelid, +3.5 ± 1.0°C vs. +2.4 ± 0.8°C; inner eyelid, +3.5 ± 1.0°C vs. +2.5 ± 0.9°C; all p < 0.001), although there was no significant difference in LLG and NIBUT improvement between treatments (all p > 0.05). A majority of subjects (78%) preferred the application of heat with the eye bag over the eye mask.Both the EyeGiene mask and the MGDRx Eye Bag are convenient eyelid warming devices that result in clinically and statistically significant increases in NIBUT and LLG in patients with mild-to-moderate dry eye symptoms. The MGDRx Eye Bag is more effective in raising ocular temperature and is the preferred treatment method among subjects. en
dc.description.uri en
dc.format.medium Print en
dc.language English en
dc.publisher Lippincott, Williams & Wilkins en
dc.relation.ispartofseries Optometry and Vision Science en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from en
dc.rights.uri en
dc.subject Eyelids en
dc.subject Meibomian Glands en
dc.subject Tears en
dc.subject Humans en
dc.subject Eyelid Diseases en
dc.subject Dry Eye Syndromes en
dc.subject Body Temperature en
dc.subject Treatment Outcome en
dc.subject Hyperthermia, Induced en
dc.subject Double-Blind Method en
dc.subject Adolescent en
dc.subject Adult en
dc.subject Female en
dc.subject Male en
dc.subject Lipid Metabolism en
dc.subject Young Adult en
dc.title Comparison of Self-applied Heat Therapy for Meibomian Gland Dysfunction en
dc.type Journal Article en
dc.identifier.doi 10.1097/opx.0000000000000601 en
pubs.issue 9 en
pubs.begin-page e321 en
pubs.volume 92 en
dc.rights.holder Copyright: Lippincott, Williams & Wilkins en
dc.identifier.pmid 25955642 en en
pubs.end-page e326 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 487004 en Medical and Health Sciences en School of Medicine en Ophthalmology Department en
dc.identifier.eissn 1538-9235 en
pubs.record-created-at-source-date 2017-08-08 en
pubs.dimensions-id 25955642 en

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